Literature DB >> 1344032

A case of human chimerism detected by unbalanced chromosomal translocation.

R H Nyberg1, A K Haapala, K O Simola.   

Abstract

Chimerism in humans is usually found only because of discrepancies in unique blood group typing or sex chromosome complements. We describe a case found because of an inherited chromosomal translocation. A female carrier of the balanced reciprocal translocation t(14;20)(q31;q13.3) had a twin pregnancy. After birth the B-twin, a girl, was found to have the balanced translocation. The A-twin, a severely malformed and stillborn boy, had two different karyotypes; a normal 46,XY and an unbalanced translocation derivative 46,XY,-14, +der(14)t(14;20)(q31;q13.3). He was a dispermic chimera, formed by two fertilized oocytes.

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Year:  1992        PMID： 1344032     DOI： 10.1111/j.1399-0004.1992.tb03251.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  3 in total

1.  Mosaicism with a normal cell line and an autosomal structural rearrangement.

Authors:  R J Gardner; H E Dockery; P H Fitzgerald; R G Parfitt; D R Romain; N Scobie; R L Shaw; P Tumewu; A J Watt
Journal:  J Med Genet       Date:  1994-02       Impact factor: 6.318

2.  Polymorphic detection of a parthenogenetic maternal and double paternal contribution to a 46,XX/46,XY hermaphrodite.

Authors:  J C Giltay; T Brunt; F A Beemer; J M Wit; H K van Amstel; P L Pearson; C Wijmenga
Journal:  Am J Hum Genet       Date:  1998-04       Impact factor: 11.025

3.  Characterization of a Rare Mosaicism in Autosomal Translocation of t(5;21) Using Conventional Cytogenetics and FISH Methods

Authors:  Sadaf Omori Sarabi; Javad Karimzad Hagh; Claudia Behrend; Seyed Behrooz Mohseni; Mitra Ansari Dezfouli; Seyed Khalil Rashidi; Mir Davood Omrani
Journal:  Iran Biomed J       Date:  2019-07-14
  3 in total

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