Literature DB >> 13416527

Narcosis and emulsion reversal by inert gases.

D F SEARS, W O FENN.   

Abstract

Investigations of the effect of high pressures of Na (100 to 130 atmospheres) and of Ar (60 to 80 atmospheres) showed that these gases are effective in reversing the phases of an oil in water emulsion. Nitrous oxide did not cause reversal at pressures as high as 53 atmospheres nor did helium as high as 107 atmospheres. We found CO(2) most effective in reversing the emulsions and attributed this to its chemical properties. It is suggested that these observations may help to explain the narcotic effects of inert gases.

Entities:  

Keywords:  ANESTHESIA, INHALATION; EMULSIONS; GASES/effects

Mesh:

Substances:

Year:  1957        PMID: 13416527      PMCID: PMC2147636          DOI: 10.1085/jgp.40.4.515

Source DB:  PubMed          Journal:  J Gen Physiol        ISSN: 0022-1295            Impact factor:   4.086


  4 in total

1.  Anesthetic action of inert and unreactive gases on intact animals and isolated tissues.

Authors:  F G CARPENTER
Journal:  Am J Physiol       Date:  1954-09

2.  Depressant action of inert gases on the central nervous system in mice.

Authors:  F G CARPENTER
Journal:  Am J Physiol       Date:  1953-02

3.  The cleavage times of fertilized eggs of the sea urchin, Arbacia punctulata, at high pressures of nitrogen, helium, and nitrous oxide.

Authors:  C HAYWOOD
Journal:  J Cell Comp Physiol       Date:  1953-04

4.  Nitrogen narcosis in frogs and mice.

Authors:  J M MARSHALL
Journal:  Am J Physiol       Date:  1951-09
  4 in total
  3 in total

1.  The affinity of narcotic agents for interfacial films.

Authors:  J A CLEMENTS; K M WILSON
Journal:  Proc Natl Acad Sci U S A       Date:  1962-06-15       Impact factor: 11.205

Review 2.  Intestinal mucous membranes: the role of the interfacial phenomena.

Authors:  D F Sears
Journal:  Agents Actions       Date:  1970-08

3.  A model representing a physiological role of CO2 at the cell membrane.

Authors:  D F SEARS; R M EISENBERG
Journal:  J Gen Physiol       Date:  1961-05       Impact factor: 4.086

  3 in total

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