Review of the clinical use of intravenous mannitol with ciguatera fish poisoning from 1988 to 1992.

Intravenous mannitol was introduced as an effective treatment for ciguatera in 1988. Clinicians have used intravenous mannitol with success in several geographic areas. However, there remains a general skepticism and reluctance to use mannitol to treat ciguatera amongst clinicians. The possible reasons for the clinician's reluctance to use intravenous mannitol to treat ciguatera are reviewed.