| Literature DB >> 1338576 |
Abstract
Phosphatidylinositol bisphosphate hydrolysis is an immediate response to many hormones, including growth factors. The hydrolysis of phosphatidylinositol bisphosphate is catalyzed by phosphatidylinositol-specific phospholipase C. A number of phospholipase C isozymes have been identified. Different isozymes are activated by different receptor classes. This review will summarize the different isozymes of phospholipase C, and the current knowledge of the mechanisms by which phospholipase C activity is modulated by growth factors.Entities:
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Year: 1992 PMID： 1338576 DOI： 10.1016/0955-2235(92)90025-d
Source DB: PubMed Journal: Prog Growth Factor Res ISSN： 0955-2235