| Literature DB >> 133813 |
Abstract
Effects of chinoform and chinoform-ferric chelate on formation of lipoperoxide in isolated sciatic nerve were investigated. Free chinoform did not increase the lipoperoxide level, while chinoform-ferric chelate significantly increased it. Assuming that the lipoperoxide formed denatures the associated protein in the nerve, the effect of chinoform-ferric chelate could explain, at least partly, the demyelination of nerve tissues caused by massive doses of chinoform.Entities:
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Year: 1976 PMID: 133813 DOI: 10.1007/bf02003759
Source DB: PubMed Journal: Experientia ISSN: 0014-4754