Literature DB >> 133757

Hot film coronary artery velocity measurements in horses.

R M Nerem, J A Rumberger, D R Gross, W W Muir, G L Geiger.   

Abstract

Coronary velocity measurements have been carried out in anaesthetized, open-chest horses using a constant-temperature, hot-film anemometer system. L-shaped needle probes inserted by direct vessel puncture have been used to measure velocity profiles in the left common, left anterior descending (LAD), and left circumflex coronary arteries. The flow conditions were characterized by peak Reynolds numbers from approximately 200 to 1500 and values of the unsteadiness parameter from 3 to 10. These measurements indicate that in the left common coronary artery the profile is in general skewed towards the outer wall as would be expected for fully viscous flow in a curved tube. In the left anterior descending and left circumflex coronary arteries just distal to the bifurcation, the skewing was found in general to be away from the flow divider. However, in regions of the LAD and left circumflex 5-6 diameters downstream of the bifurcation, the peak systolic and diastolic profiles were indicative of a more fully developed, Poiseuille type flow with only slight skewing observed. The results of this study indicate that the flow in the coronary system, though in general laminar and disturbance free, is extremely varied in character and may exhibit large amplitude, low frequency flow oscillations. Furthermore, for these vessels which all lie on the surface of the myocardium, large systolic flows were observed to be present, even though the major portion of the volume flow was reserved for the diastolic period.

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Year:  1976        PMID: 133757     DOI: 10.1093/cvr/10.3.301

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN: 0008-6363            Impact factor:   10.787


  2 in total

1.  Measurement of point velocity in the canine coronary artery by laser Doppler velocimeter with optical fiber.

Authors:  G Tomonaga; H Mitake; N Hoki; F Kajiya
Journal:  Jpn J Surg       Date:  1981

2.  Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells.

Authors:  Xiaomei Qin; Jianwei Tian; Peng Zhang; Yanbo Fan; Li Chen; Youfei Guan; Yi Fu; Yi Zhu; Shu Chien; Nanping Wang
Journal:  Cardiovasc Res       Date:  2007-02-20       Impact factor: 10.787

  2 in total

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