Literature DB >> 1337461

Structure of bluetongue virus particles by cryoelectron microscopy.

E A Hewat1, T F Booth, P Roy.   

Abstract

The structure of the bluetongue virus (BTV) particle, determined by cryoelectron microscopy and image analysis, reveals a well-ordered outer shell which differs markedly from other known Reoviridae. The inner shell is known to have an icosahedral structure with 260 triangular spikes of VP7 trimers arranged on a T = 13,l lattice. The outer shell is seen to consist of 120 globular regions (possibly VP5), which sit neatly on each of the six-membered rings of VP7 trimers. "Sail"-shaped spikes located above 180 of the VP7 trimers form 60 triskelion-type motifs which cover all but 20 of the VP7 trimers. These spikes are possibly the hemagglutinating protein VP2 which contains a virus neutralization epitope. Thus, VP2 and VP5 together form a continuous layer around the inner shell except for holes on the 5-fold axis.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1337461     DOI： 10.1016/1047-8477(92)90068-l

Source DB:  PubMed          Journal:  J Struct Biol        ISSN： 1047-8477            Impact factor:   2.867


  29 in total

Review 1.  Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs.

Authors:  T S Baker; N H Olson; S D Fuller
Journal:  Microbiol Mol Biol Rev       Date:  1999-12       Impact factor: 11.056

2.  A capsid protein of nonenveloped Bluetongue virus exhibits membrane fusion activity.

Authors:  Mario Forzan; Christoph Wirblich; Polly Roy
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-04       Impact factor: 11.205

3.  Intermediates in the assembly pathway of the double-stranded RNA virus phi6.

Authors:  S J Butcher; T Dokland; P M Ojala; D H Bamford; S D Fuller
Journal:  EMBO J       Date:  1997-07-16       Impact factor: 11.598

4.  Structural insight into African horsesickness virus infection.

Authors:  Violeta Manole; Pasi Laurinmäki; Wouter Van Wyngaardt; Christiaan A Potgieter; Isabella M Wright; Gert J Venter; Alberdina A van Dijk; B Trevor Sewell; Sarah J Butcher
Journal:  J Virol       Date:  2012-05-16       Impact factor: 5.103

5.  Topography and immunogenicity of bluetongue virus VP7 epitopes.

Authors:  L F Wang; A D Hyatt; P L Whiteley; M Andrew; J K Li; B T Eaton
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

6.  Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction.

Authors:  K A Dryden; G Wang; M Yeager; M L Nibert; K M Coombs; D B Furlong; B N Fields; T S Baker
Journal:  J Cell Biol       Date:  1993-09       Impact factor: 10.539

7.  The membrane trafficking protein calpactin forms a complex with bluetongue virus protein NS3 and mediates virus release.

Authors:  Andrew R Beaton; Javier Rodriguez; Y Krishnamohan Reddy; Polly Roy
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-16       Impact factor: 11.205

8.  Interactions between the inner and outer capsids of bluetongue virus.

Authors:  Emma L Nason; Rosalba Rothagel; Sharmila K Mukherjee; Alak Kanti Kar; Mario Forzan; B V Venkataram Prasad; Polly Roy
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

9.  RT-PCR assays for seven serotypes of epizootic haemorrhagic disease virus & their use to type strains from the Mediterranean region and North America.

Authors:  Narender S Maan; Sushila Maan; Kyriaki Nomikou; Donna J Johnson; Mehdi El Harrak; Hafsa Madani; Hagai Yadin; Serife Incoglu; Kadir Yesilbag; Andrew B Allison; David E Stallknecht; Carrie Batten; Simon J Anthony; Peter P C Mertens
Journal:  PLoS One       Date:  2010-09-17       Impact factor: 3.240

10.  Identification of domains in bluetongue virus VP3 molecules essential for the assembly of virus cores.

Authors:  S Tanaka; P Roy
Journal:  J Virol       Date:  1994-05       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.