| Literature DB >> 1335599 |
G Kweifio-Okai1, T A Macrides.
Abstract
Triterpenes--alpha-amyrin acetate, beta-amyrin acetate and beta-amyrin were tested for their effects on the synthesis of 5-lipoxygenase products in human neutrophils. All the triterpenes reduced 5-HETE synthesis without effect on LTB4 synthesis. The relative effects suggest that 5-HETE inhibition can explain the antiarthritic activity possessed by these compounds.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1335599
Source DB: PubMed Journal: Res Commun Chem Pathol Pharmacol ISSN： 0034-5164