Literature DB >> 13355866

The mechanism of the reaction of chymotrypsin with p-nitrophenyl acetate.

H GUTFREUND, J M STURTEVANT.   

Abstract

Entities:  

Keywords:  NITROBENZENE/related compounds; PROTEASES

Mesh：

Substances：

Year:  1956        PMID： 13355866      PMCID： PMC1216234          DOI： 10.1042/bj0630656

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


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  5 in total

1.  Two steps in the reaction of chymotrypsin with acetyl-L-phenylalanine ethyl ester.

Authors:  B R HAMMOND; H GUTFREUND
Journal:  Biochem J       Date:  1955-10       Impact factor: 3.857

2.  The reaction of p-nitrophenyl esters with chymotrypsin and insulin.

Authors:  B S HARTLEY; B A KILBY
Journal:  Biochem J       Date:  1954-02       Impact factor: 3.857

3.  Serine phosphoric acid from diisopropylphosphoryl chymotrypsin.

Authors:  N K SCHAFFER; S C MAY; W H SUMMERSON
Journal:  J Biol Chem       Date:  1953-05       Impact factor: 5.157

4.  THE inhibition of chymotrypsin by diethyl p-nitrophenyl phosphate.

Authors:  B S HARTLEY; B A KILBY
Journal:  Biochem J       Date:  1952-03       Impact factor: 3.857

5.  Stoichiometric inhibition of chymotrypsin.

Authors:  A K BALLS; E F JANSEN
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1952
  5 in total
  31 in total

1.  PROPERTIES OF A BLOCKED TETRAPEPTIDE ANALOGUE OF THE ACTIVE SITE OF SUBTILISIN.

Authors:  S BERNHARD; Z GRDINIC; H NOLLER; N SHALTIEL
Journal:  Proc Natl Acad Sci U S A       Date:  1964-12       Impact factor: 11.205

2.  Conformational changes in enzyme catalysis.

Authors:  B LABOUESSE; B H HAVSTEEN; G P HESS
Journal:  Proc Natl Acad Sci U S A       Date:  1962-12-15       Impact factor: 11.205

3.  Steps in the reactions of chymotrypsin with tyrosine derivatives.

Authors:  H GUTFREUND; B R HAMMOND
Journal:  Biochem J       Date:  1959-11       Impact factor: 3.857

4.  Deacetylcephalosporin C.

Authors:  J D JEFFERY; E P ABRAHAM; G G NEWTON
Journal:  Biochem J       Date:  1961-12       Impact factor: 3.857

5.  The active site and mechanism of action of bovine pancreatic ribonuclease. 6. Kinetic and spectrophotometric investigation of the interaction of the enzyme with inhibitors and p-nitrophenyl acetate.

Authors:  C A Ross; A P Mathias; B R Rabin
Journal:  Biochem J       Date:  1962-10       Impact factor: 3.857

6.  THE MECHANISM OF CHYMOTRYPSIN-CATALYZED REACTIONS.

Authors:  H Gutfreund; J M Sturtevant
Journal:  Proc Natl Acad Sci U S A       Date:  1956-10       Impact factor: 11.205

7.  Kinetic parameters of the acyl-enzyme mechanism and conditions for quasi-equilibrium and for optimal catalytic characteristics.

Authors:  K Brocklehurst; C M Topham
Journal:  Biochem J       Date:  1990-09-01       Impact factor: 3.857

8.  Determination of half-reaction equilibrium in a ping-pong enzyme mechanism.

Authors:  G D Smith; R Harrison; R Eisenthal
Journal:  Neurochem Res       Date:  1996-09       Impact factor: 3.996

9.  The kinetics of acylation and deacylation of penicillin acylase from Escherichia coli ATCC 11105: evidence for lowered pKa values of groups near the catalytic centre.

Authors:  M Morillas; M L Goble; R Virden
Journal:  Biochem J       Date:  1999-02-15       Impact factor: 3.857

10.  Catalytic and ligand binding properties of bovine trypsinogen and its complex with the effector dipeptide Ile-Val. A comparative study.

Authors:  E Antonini; P Ascenzi; M Bolognesi; M Guarneri; E Menegatti; G Amiconi
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396
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