Literature DB >> 1335275

Macrophage association of polyomavirus in progressive multifocal leukoencephalopathy: an immunohistochemical and ultrastructural study. Case report.

R Mesquita1, C Parravicini, M Björkholm, M Ekman, P Biberfeld.   

Abstract

Progressive multifocal leukoencephalopathy (PML) in a patient following autologous bone marrow transplantation for a non-Hodgkin's centroblastic lymphoma was studied by immunohistochemistry and transmission electron microscopy. Our observations indicate that a large amount of polyomavirus, most probably JC virus, is taken up and segregated within vacuoles of macrophages by phagocytosis. A relevant role of macrophages in the pathogenesis of PML is emphasized.

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Year:  1992        PMID: 1335275     DOI: 10.1111/j.1699-0463.1992.tb04031.x

Source DB:  PubMed          Journal:  APMIS        ISSN: 0903-4641            Impact factor:   3.205


  4 in total

1.  Progressive multifocal leukoencephalopathy in transplant recipients.

Authors:  Farrah J Mateen; RajaNandini Muralidharan; Marco Carone; Diederik van de Beek; Daniel M Harrison; Allen J Aksamit; Mary S Gould; David B Clifford; Avindra Nath
Journal:  Ann Neurol       Date:  2011-08       Impact factor: 10.422

2.  Association of simian virus 40 with a central nervous system lesion distinct from progressive multifocal leukoencephalopathy in macaques with AIDS.

Authors:  M A Simon; P O Ilyinskii; G B Baskin; H Y Knight; D R Pauley; A A Lackner
Journal:  Am J Pathol       Date:  1999-02       Impact factor: 4.307

3.  New JC virus infection patterns by in situ polymerase chain reaction in brains of acquired immunodeficiency syndrome patients with progressive multifocal leukoencephalopathy.

Authors:  Regina W von Einsiedel; Ingrid W Samorei; Michael Pawlita; Baerbel Zwissler; Max Deubel; Harry V Vinters
Journal:  J Neurovirol       Date:  2004-02       Impact factor: 2.643

4.  Drug-associated progressive multifocal leukoencephalopathy: a clinical, radiological, and cerebrospinal fluid analysis of 326 cases.

Authors:  Roderick P P W M Maas; Annemarie H G Muller-Hansma; Rianne A J Esselink; Jean-Luc Murk; Clemens Warnke; Joep Killestein; Mike P Wattjes
Journal:  J Neurol       Date:  2016-07-11       Impact factor: 4.849

  4 in total

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