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Literature DB >> 1334834

Epstein-Barr virus infection and associated diseases in children. II. Diagnostic and therapeutic strategies.

Abstract

Epstein-Barr virus (EBV), an ubiquitous human B lymphotropic virus, is the cause of infectious mononucleosis. Moreover, EBV infection can be followed by lymphoproliferative diseases in patients with inherited and acquired immunodeficiencies. Primary EBV infection may be a threat to all children after marrow or organ transplantation or those receiving chronic immunosuppressive treatment for various other reasons. The virus has been also implicated in the pathogenesis of different malignant tumours such as Burkitt lymphoma, nasopharyngeal carcinoma, Hodgkin disease and also some T-cell lymphomas. This review focuses on various aspects of virus-host interactions, immune mechanisms of the host, and the still experimental therapeutic approaches in EBV-associated diseases.

Entities: Disease Species

Mesh：

Substances：
Antibodies, Viral

Year: 1992 PMID： 1334834 DOI： 10.1007/bf01957926

Source DB: PubMed Journal: Eur J Pediatr ISSN： 0340-6199 Impact factor: 3.183

44 in total

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Authors: L Resnick; J S Herbst; D V Ablashi; S Atherton; B Frank; L Rosen; S N Horwitz
Journal: JAMA Date: 1988-01-15 Impact factor: 56.272

3. Treatment of severe Epstein-Barr virus-induced polyclonal B-lymphocyte proliferation by anti-B-cell monoclonal antibodies. Two cases after HLA-mismatched bone marrow transplantation.

Authors: S Blanche; F Le Deist; F Veber; G Lenoir; A M Fischer; J Brochier; C Boucheix; M Delaage; C Griscelli; A Fischer
Journal: Ann Intern Med Date: 1988-02 Impact factor: 25.391

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Authors: J L Sullivan; P Medveczky; S J Forman; S M Baker; J E Monroe; C Mulder
Journal: N Engl J Med Date: 1984-11-01 Impact factor: 91.245

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Journal: N Engl J Med Date: 1982-04-15 Impact factor: 91.245

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Journal: Proc Natl Acad Sci U S A Date: 1987-01 Impact factor: 11.205

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Authors: D W Hanto; J S Najarian
Journal: J Surg Oncol Date: 1985-12 Impact factor: 3.454

Review 8. Management of Epstein-Barr virus infections.

Authors: J Andersson; I Ernberg
Journal: Am J Med Date: 1988-08-29 Impact factor: 4.965

9. Anti-B-cell monoclonal antibodies in the treatment of severe B-cell lymphoproliferative syndrome following bone marrow and organ transplantation.

Authors: A Fischer; S Blanche; J Le Bidois; P Bordigoni; J L Garnier; P Niaudet; F Morinet; F Le Deist; A M Fischer; C Griscelli
Journal: N Engl J Med Date: 1991-05-23 Impact factor: 91.245

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Authors: B Z Katz; N Raab-Traub; G Miller
Journal: J Infect Dis Date: 1989-10 Impact factor: 5.226

5 in total

1. Application of virus-specific immunoglobulin M (IgM), IgG, and IgA antibody detection with a polyantigenic enzyme-linked immunosorbent assay for diagnosis of Epstein-Barr virus infections in childhood.

Authors: L Schaade; M Kleines; M Häusler
Journal: J Clin Microbiol Date: 2001-11 Impact factor: 5.948

2. Epstein-Barr virus associated lymphoproliferative disorder with fatal involvement of the gastrointestinal tract in an infant.

Authors: L X Pan; P Ramani; T C Diss; L N Liang; P G Isaacson
Journal: J Clin Pathol Date: 1995-04 Impact factor: 3.411