Literature DB >> 1334602

Antisense oligonucleotides: inhibition of liver cell proliferation and in vivo disposition.

M Inagaki1, K Togawa, B I Carr, K Ghosh, J S Cohen.   

Abstract

As oligomers inhibited hepatoma growth in vitro. These cells have oligomer-specific binding sites. The oligomers were taken up by liver and have potential for hepatic growth modulation in intact animals.

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Year:  1992        PMID： 1334602

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


  4 in total

1.  Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo.

Authors:  E A Biessen; H Vietsch; E T Rump; K Fluiter; J Kuiper; M K Bijsterbosch; T J van Berkel
Journal:  Biochem J       Date:  1999-06-15       Impact factor: 3.857

Review 2.  Gene modulation for treating liver fibrosis.

Authors:  Kun Cheng; Ram I Mahato
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  2007       Impact factor: 4.889

Review 3.  Pharmacokinetics of antisense oligonucleotides.

Authors:  S Agrawal; J Temsamani; W Galbraith; J Tang
Journal:  Clin Pharmacokinet       Date:  1995-01       Impact factor: 6.447

4.  Synthesis of 3H-labeled nucleoside-methyl[CT3]phosphonamidite and incorporation into methylphosphonate oligonucleotides for biodistribution and biostability studies.

Authors:  M M Vaghefi; R C Fazio; K M Young; W B Marvin
Journal:  Nucleic Acids Res       Date:  1995-09-11       Impact factor: 16.971
  4 in total

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