Literature DB >> 1334056

Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis.

M Murakoshi1, H Nishino, H Tokuda, A Iwashima, J Okuzumi, H Kitano, R Iwasaki.   

Abstract

Squalene inhibited the effect of tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA), such as increased 32Pi incorporation into phospholipids of HeLa cell membrane, induction of Epstein-Barr-virus early antigen in Raji cell and induction of ornithine decarboxylase in mouse skin. Squalene also markedly suppressed the promoting activity of TPA on skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated mice.

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Year:  1992        PMID： 1334056     DOI： 10.1002/ijc.2910520620

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  10 in total

1.  High-level recombinant production of squalene using selected Saccharomyces cerevisiae strains.

Authors:  Jong Yun Han; Sung Hwa Seo; Jae Myeong Song; Hongweon Lee; Eui-Sung Choi
Journal:  J Ind Microbiol Biotechnol       Date:  2018-02-02       Impact factor: 3.346

2.  Squalene selectively protects mouse bone marrow progenitors against cisplatin and carboplatin-induced cytotoxicity in vivo without protecting tumor growth.

Authors:  Bikul Das; Roula Antoon; Rika Tsuchida; Shamim Lotfi; Olena Morozova; Walid Farhat; David Malkin; Gideon Koren; Herman Yeger; Sylvain Baruchel
Journal:  Neoplasia       Date:  2008-10       Impact factor: 5.715

3.  Hepatic subcellular distribution of squalene changes according to the experimental setting.

Authors:  Roberto Martínez-Beamonte; Olga Alda; Teresa Sanclemente; María J Felices; Sara Escusol; Carmen Arnal; Luis V Herrera-Marcos; Sonia Gascón; Joaquín C Surra; Jesús Osada; Mª Jesús Rodríguez-Yoldi
Journal:  J Physiol Biochem       Date:  2018-02-22       Impact factor: 4.158

4.  Increased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory response.

Authors:  Jacqueline Surls; Cristina Nazarov-Stoica; Margaret Kehl; Cara Olsen; Sofia Casares; Teodor-D Brumeanu
Journal:  PLoS One       Date:  2012-06-19       Impact factor: 3.240

5.  Modulating Effect of Enicostemma littorale on the Expression Pattern of Apoptotic, Cell Proliferative, Inflammatory and Angiogenic Markers During 7, 12-Dimethylbenz (a) Anthracene Induced Hamster Buccal Pouch Carcinogenesis.

Authors:  Shanmugam Manoharan; Duraisamy Rajasekaran; Murugaraj Manoj Prabhakar; Sekar Karthikeyan; Asokan Manimaran
Journal:  Toxicol Int       Date:  2015 Jan-Apr

6.  Clinacanthus Nutans Hexane Extracts Induce Apoptosis Through a Caspase-Dependent Pathway in Human Cancer Cell Lines

Authors:  Pei Ying Ng; Soi Moi Chye; Chew Hee Ng; Rhun Yian Koh; Yee Lian Tiong; Liew Phing Pui; Yong Hui Tan; Crystale Siew Ying Lim; Khuen Yen Ng
Journal:  Asian Pac J Cancer Prev       Date:  2017-04-01

Review 7.  Therapeutic Potential and Nutraceutical Profiling of North Bornean Seaweeds: A Review.

Authors:  Muhammad Dawood Shah; Balu Alagar Venmathi Maran; Sitti Raehanah Muhamad Shaleh; Wahidatul Husna Zuldin; Charles Gnanaraj; Yoong Soon Yong
Journal:  Mar Drugs       Date:  2022-01-25       Impact factor: 5.118

8.  Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase.

Authors:  Naoto Tatewaki; Tetsuya Konishi; Yuki Nakajima; Miyako Nishida; Masafumi Saito; Takahiro Eitsuka; Toshiyuki Sakamaki; Nobuo Ikekawa; Hiroshi Nishida
Journal:  PLoS One       Date:  2016-01-29       Impact factor: 3.240

9.  Effects of a synbiotic on the fecal microbiome and metabolomic profiles of healthy research cats administered clindamycin: a randomized, controlled trial.

Authors:  Jacqueline C Whittemore; Jennifer E Stokes; Joshua M Price; Jan S Suchodolski
Journal:  Gut Microbes       Date:  2019-02-01

10.  Squalene Loaded Nanoparticles Effectively Protect Hepatic AML12 Cell Lines against Oxidative and Endoplasmic Reticulum Stress in a TXNDC5-Dependent Way.

Authors:  Seyed Hesamoddin Bidooki; Teresa Alejo; Javier Sánchez-Marco; Roberto Martínez-Beamonte; Roubi Abuobeid; Juan Carlos Burillo; Roberto Lasheras; Victor Sebastian; María J Rodríguez-Yoldi; Manuel Arruebo; Jesús Osada
Journal:  Antioxidants (Basel)       Date:  2022-03-18
  10 in total

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