Literature DB >> 1333973

The effect of nedocromil sodium on the isolated rabbit vagus nerve.

D M Jackson1, C E Pollard, S M Roberts.   

Abstract

Nedocromil sodium depolarized the isolated rabbit vagus nerve. The depolarization was blocked by DIDS (4,4'-diisothiocyanostilbene-2,2'-disulphonic acid) and did not occur when the nerve was bathed in solutions low in chloride. After depolarization the nerve was refractory to nedocromil sodium for an hour. It is suggested that nedocromil sodium can affect a chloride channel.

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Year:  1992        PMID: 1333973     DOI: 10.1016/0014-2999(92)90790-b

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  3 in total

1.  Nedocromil sodium inhibits histamine-induced itch and flare in human skin.

Authors:  P Ahluwalia; J I McGill; M K Church
Journal:  Br J Pharmacol       Date:  2001-02       Impact factor: 8.739

2.  Diuretics and asthma.

Authors:  P J Barnes
Journal:  Thorax       Date:  1993-03       Impact factor: 9.139

3.  Effect of loop diuretics on cholinergic neurotransmission in human airways in vitro.

Authors:  G M Verleden; J L Pype; G Deneffe; M G Demedts
Journal:  Thorax       Date:  1994-07       Impact factor: 9.139

  3 in total

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