| Literature DB >> 1333265 |
Abstract
Genes responsible for the hereditary predisposition to a variety of human cancers have now been isolated. Their function seems to be part of complex signalling pathways involved in the control of cellular differentiation and the cell cycle. The presence of a single copy of these genes appears to be sufficient to ensure normal development, i.e. prevents tumorigenesis, and has earned them the name--tumour suppressor genes.Entities:
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Year: 1992 PMID： 1333265 DOI： 10.1093/oxfordjournals.annonc.a058319
Source DB: PubMed Journal: Ann Oncol ISSN： 0923-7534 Impact factor: 32.976