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Literature DB >> 13329850

The Treponema pallidum immobilization test.

Abstract

The authors first discuss the principle of the Treponema pallidum immobilization (TPI) test, considered both as a qualitative and as a quantitative test, and then various specific aspects of passage of the Nichols strain of treponeme in rabbit testes. A number of important technical details and modifications in the test procedure are then reviewed, and the clinical value of the test is discussed.The sensitivity of the TPI test is considerably greater than that of the serological tests for syphilis more usually performed, and its specificity is also remarkably high. However, it is stressed that, at the present stage of development, the greatest value of the TPI test lies in its use as an excellent aid to diagnosis rather than as a test of cure.

Entities: Species

Keywords: SYPHILIS/diagnosis

Mesh：

Year: 1956 PMID： 13329850 PMCID： PMC2538021

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

62 in total

1. [Significance of the Nelson test in the modern serodiagnosis of syphilis; personal experiences with 450 Nelson's tests].

Authors: R DOEPFMER; A GREIFELT; K GREGORCZYK
Journal: Z Hyg Infektionskr Date: 1954

2. Latent syphilis ignorée and syphilis control during the epidemic in Denmark, 1942 to 1949; a statistical analysis of newly diagnosed untreated cases.

Authors: I B SVENDSEN
Journal: Am J Syph Gonorrhea Vener Dis Date: 1953-11

3. A study of the Treponema immobilizing antibody in syphilis.

Authors: C W CHACKO
Journal: Br J Exp Pathol Date: 1953-10

4. A modification of the Nelson treponemal sustaining medium for use in the Treponema pallidum immobilization test.

Authors: V R SAURINO
Journal: Am J Syph Gonorrhea Vener Dis Date: 1953-03

5. [Study of the factors interfering in the reaction of the Nelson-Mayer immobilization test. I. Possible anticomplementary capacity of the culture medium].

Authors: J THIVOLET; M ROLLAND
Journal: Ann Biol Clin (Paris) Date: 1953 May-Jun Impact factor: 0.459

4. TPI Test in Untreated Syphilis: A SEROLOGICAL RE-EXAMINATION OF 50 PATIENTS BELONGING TO "THE OSLO STUDY OF UNTREATED SYPHILIS".

Authors: J Eng; K Wereide
Journal: Br J Vener Dis Date: 1962-12

5. Biological false positive reactions in treponemal serological tests used to diagnose syphilis.

Authors: C S Petersen
Journal: Genitourin Med Date: 1986-10

6. [The relationship between immobilizing antibodies of serum and cerebrospinal fluid. Studies with the standardized treponema pallidum immobilizing (TPI) test on matched serum samples].

Authors: F Müller; M Kruska; H Hippius
Journal: Z Neurol Date: 1970

7. A simplified method of performing the Treponema pallidum immobilization test.

Authors: N M Ovcinnikov
Journal: Bull World Health Organ Date: 1965 Impact factor: 9.408

Review 8. Anticoagulation in management of antiphospholipid antibody syndrome in pregnancy.

Authors: Michael D Lockshin
Journal: Clin Lab Med Date: 2013-04-19 Impact factor: 1.935

9. Enzyme-linked immunosorbent assay for detection of immunoglobulin M antibody against the Reiter treponeme flagellum in syphilis.

Authors: N S Pedersen; C S Petersen; N H Axelsen
Journal: J Clin Microbiol Date: 1982-10 Impact factor: 5.948

9 in total

The Treponema pallidum immobilization test.

1. [Significance of the Nelson test in the modern serodiagnosis of syphilis; personal experiences with 450 Nelson's tests].

2. Latent syphilis ignorée and syphilis control during the epidemic in Denmark, 1942 to 1949; a statistical analysis of newly diagnosed untreated cases.

3. A study of the Treponema immobilizing antibody in syphilis.

4. A modification of the Nelson treponemal sustaining medium for use in the Treponema pallidum immobilization test.

5. [Study of the factors interfering in the reaction of the Nelson-Mayer immobilization test. I. Possible anticomplementary capacity of the culture medium].

6. A study of pinta in the Tepalcatepec Basin, Michoacan, Mexico. I. Field identification of the disease.

7. [The Nelson test and killed Treponema].

8. The specificity of the treponemal immobilization test.

9. The role of temperature in experimental treponemal infection.

10. Immobilization of Treponema pallidum in vitro by antibody produced in syphilitic infection.

1. The fluorescent treponemal antibody test in the serological diagnosis of syphilis.

2. A clinical assessment of the treponemal Wassermann reaction.