Literature DB >> 1331926

The molecular basis of the inhibition of collagenase by vitamin A.

G Wolf1.   

Abstract

Retinoic acid inhibits the enzyme collagenase by forming an inactive complex between the liganded nuclear retinoic acid receptors and c-Jun, a protein that is itself an activator of the collagenase gene.

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Year:  1992        PMID: 1331926     DOI: 10.1111/j.1753-4887.1992.tb02468.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN: 0029-6643            Impact factor:   7.110


  2 in total

1.  Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy?

Authors:  D J Buttle; H Bramwell; A P Hollander
Journal:  Clin Mol Pathol       Date:  1995-08

2.  Platelet-activating factor induces collagenase expression in corneal epithelial cells.

Authors:  H E Bazan; Y Tao; N G Bazan
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-15       Impact factor: 11.205

  2 in total

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