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Literature DB >> 1330694

Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain.

Y Hakamata¹, J Nakai, H Takeshima, K Imoto.

Abstract

The complete amino acid sequence of a novel ryanodine receptor/calcium release channel from rabbit brain has been deduced by cloning and sequence analysis of the cDNA. This protein is composed of 4872 amino acids and shares characteristic structural features with the skeletal muscle and cardiac ryanodine receptors. RNA blot hybridization analysis shows that the brain ryanodine receptor is abundantly expressed in corpus striatum, thalamus and hippocampus, whereas the cardiac ryanodine receptor is more uniformly expressed in the brain. The brain ryanodine receptor gene is transcribed also in smooth muscle.

Entities: Gene Mutation Species

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Year: 1992 PMID： 1330694 DOI： 10.1016/0014-5793(92)80941-9

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

103 in total

Review 1. Dynamic regulation of intracellular calcium signals through calcium release channels.

Authors: M Iino
Journal: Mol Cell Biochem Date: 1999-01 Impact factor: 3.396

2. Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers.

Authors: S O Marx; S Reiken; Y Hisamatsu; M Gaburjakova; J Gaburjakova; Y M Yang; N Rosemblit; A R Marks
Journal: J Cell Biol Date: 2001-05-14 Impact factor: 10.539

3. Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus.

Authors: Z Liu; J Zhang; M R Sharma; P Li; S R Chen; T Wagenknecht
Journal: Proc Natl Acad Sci U S A Date: 2001-05-15 Impact factor: 11.205

4. Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

Authors: Michael A Grillo; Stephanie L Grillo; Bryan C Gerdes; Jacob G Kraus; Peter Koulen
Journal: Mol Neurobiol Date: 2018-05-05 Impact factor: 5.590

5. Identification of novel missense mutations of cardiac ryanodine receptor gene in exercise-induced sudden death at autopsy.

Authors: Wendy Creighton; Renu Virmani; Robert Kutys; Allen Burke
Journal: J Mol Diagn Date: 2006-02 Impact factor: 5.568

Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain.

Review 1. Dynamic regulation of intracellular calcium signals through calcium release channels.

2. Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers.

3. Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus.

4. Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

5. Identification of novel missense mutations of cardiac ryanodine receptor gene in exercise-induced sudden death at autopsy.

6. Multiple isoforms of the ryanodine receptor are expressed in rat pancreatic acinar cells.

7. Sulfhydryl oxidation modifies the calcium dependence of ryanodine-sensitive calcium channels of excitable cells.

Review 8. Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

9. CCDI: a new ligand that modulates mammalian type 1 ryanodine receptor (RyR1).

10. Resveratrol Directly Controls the Activity of Neuronal Ryanodine Receptors at the Single-Channel Level.