Literature DB >> 1330420

In vitro activity of l-ofloxacin against norfloxacin-resistant coagulase-negative staphylococci.

B Foleno1, K P Fu.   

Abstract

The in vitro activity of l-ofloxacin was determined against coagulase-negative staphylococci that were induced to norfloxacin resistance. l-Ofloxacin was the most active agent tested with an MIC90 of 4 micrograms/ml compared with greater than 128, 32, and 128 micrograms/ml for norfloxacin, ciprofloxacin, and enoxacin, respectively. Rifampin-resistant, coagulase-negative staphylococci were not cross-resistant to the quinolones tested. Among the rifampin-resistant organisms tested, l-ofloxacin was also the most active agent with an MIC90 of 0.25 micrograms/ml.

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Year:  1992        PMID： 1330420     DOI： 10.1016/0732-8893(92)90109-7

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  4 in total

1.  Interpretive criteria and quality control for antimicrobial susceptibility tests of levofloxacin.

Authors:  A Barry; P Fuchs; F Tenover; S Allen; D Hardy; J Jorgensen; J McLaughlin; L Reller
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1994-10       Impact factor: 3.267

Review 2.  Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.

Authors:  S S Patel; C M Spencer
Journal:  Drugs       Date:  1996-01       Impact factor: 9.546

3.  Prevalence of resistance to three fluoroquinolones: assessment of levofloxacin disk test error rates and surrogate predictors of levofloxacin susceptibility. AST Surveillance Group.

Authors:  P C Fuchs; A L Barry; S D Brown
Journal:  Antimicrob Agents Chemother       Date:  1996-07       Impact factor: 5.191

4.  Levofloxacin disk potency and tentative interpretive criteria for susceptibility tests.

Authors:  M A Pfaller; A L Barry; P C Fuchs
Journal:  J Clin Microbiol       Date:  1993-07       Impact factor: 5.948
  4 in total

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