| Literature DB >> 132915 |
R Kartzinel, R D Hunt, D B Calne.
Abstract
Following a recent report that apomorphine hydrochloride alleviates the involuntary movements of Huntington chorea, we have investigated another dopamine receptor agonist, bromocriptine, in this disease. A double-blind crossover study in six patients showed that rather than improving chorea, bromocriptine induced an exacerbation. This finding supports the view that choreatic movements correlate with overactivity in dopaminergic systems.Entities:
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Year: 1976 PMID： 132915 DOI： 10.1001/archneur.1976.00500070059012
Source DB: PubMed Journal: Arch Neurol ISSN： 0003-9942