| Literature DB >> 1328265 |
K D Riedel1, A Wildfeuer, H Laufen, T Zimmermann.
Abstract
Two sensitive methods for the determination of the azalide antibiotic azithromycin in human serum were compared. High-performance liquid chromatography (HPLC) and a microbiological assay were simultaneously applied to 768 serum samples obtained in a clinical study. There was excellent agreement between the azithromycin concentrations measured by HPLC and by the bioassay. The correlation coefficient for the two methods was r2 = 0.96. The precision and the sensitivity of the methods were found to be very similar.Entities:
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Year: 1992 PMID： 1328265 DOI： 10.1016/0378-4347(92)80212-9
Source DB: PubMed Journal: J Chromatogr