Literature DB >> 1327877

Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria.

E Estornell1, R Fato, C Castelluccio, M Cavazzoni, G Parenti Castelli, G Lenaz.   

Abstract

The saturation kinetics of NADH and succinate oxidation for Coenzyme Q (CoQ) has been re-investigated in pentane-extracted lyophilized beef heart mitochondria reconstituted with exogenous CoQ10. The apparent 'Km' for CoQ10 was one order of magnitude lower in succinate cytochrome c reductase than in NADH cytochrome c reductase. The Km value in NADH oxidation approaches the natural CoQ content of beef heart mitochondria, whereas that in succinate oxidation is close to the content of respiratory chain enzymes.

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Year:  1992        PMID： 1327877     DOI： 10.1016/0014-5793(92)81378-y

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  25 in total

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8.  Role of mitochondrial complex I and protective effect of CoQ10 supplementation in propofol induced cytotoxicity.

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Review 9.  Coenzyme Q, oxidative stress and aging.

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10.  Hydroquinone peroxidase activity of maize root mitochondria.

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