Literature DB >> 13271678

A method for coupling protein antigens to erythrocytes. II. Use of the method in the diagnosis of tuberculosis.

L R COLE, J J MATLOFF, V R FARRELL.   

Abstract

A serological technique, using formalinized red cells coupled to tuberculin PPD as antigen, has been assayed in a trial series of 124 tuberculous and 139 non-tuberculous patients. The stability of the antigen preparation, and the omission of an adsorption procedure for the removal of isoagglutinins facilitated the performance of the test. The results indicate that the technique warrants further trial as a diagnostic criterion of infection tuberculosis.

Entities:  

Keywords:  BENZIDINE; ERYTHROCYTES; TUBERCULIN

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Substances:

Year:  1955        PMID: 13271678      PMCID: PMC2136544          DOI: 10.1084/jem.102.6.647

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  4 in total

1.  A serological test in tuberculosis; experimental and clinical observations.

Authors:  S ROTHBARD
Journal:  Med Clin North Am       Date:  1951-03       Impact factor: 5.456

2.  Antigens of tubercle bacillus involved in hemagglutination and hemolysis reactions.

Authors:  G MIDDLEBROOK
Journal:  Bull N Y Acad Med       Date:  1952-07

3.  A method for coupling protein antigens to erythrocytes. I. Description of method.

Authors:  L R COLE; V R FARRELL
Journal:  J Exp Med       Date:  1955-12-01       Impact factor: 14.307

4.  Specific serum agglutination of erythrocytes sensitized with extracts of tubercle bacilli.

Authors:  G MIDDLEBROOK; R J DUBOS
Journal:  J Exp Med       Date:  1948-11       Impact factor: 14.307

  4 in total

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