Literature DB >> 1326945

Functional difference between SERCA2a and SERCA2b Ca2+ pumps and their modulation by phospholamban.

H Verboomen1, F Wuytack, H De Smedt, B Himpens, R Casteels.   

Abstract

COS 1 cells were transfected with full-length pig stomach sarcoplasmic/endoplasmic reticulum Ca2+ pump (SERCA)2a or SERCA2b cDNA. Ca2+ uptake by microsomes from transfected cells revealed that the Ca2+ affinity of the SERCA2b Ca2+ pump (K0.5 0.17 +/- 0.01 microM) was higher than that of the SERCA2a Ca2+ pump (K0.5 0.31 +/- 0.02 microM). Thapsigargin-sensitivity was found to be identical for the two isoforms. The Ca2+ affinity of both the SERCA2a and SERCA2b Ca2+ pumps was decreased by a factor of two when they were co-expressed with phospholamban.

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Year:  1992        PMID： 1326945      PMCID： PMC1132938          DOI： 10.1042/bj2860591

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  33 in total

1.  Evidence for two isoforms of the endoplasmic-reticulum Ca2+ pump in pig smooth muscle.

Authors:  J A Eggermont; F Wuytack; S De Jaegere; L Nelles; R Casteels
Journal:  Biochem J       Date:  1989-06-15       Impact factor: 3.857

2.  cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump.

Authors:  S E Burk; J Lytton; D H MacLennan; G E Shull
Journal:  J Biol Chem       Date:  1989-11-05       Impact factor: 5.157

3.  Localization of phospholamban in slow but not fast canine skeletal muscle fibers. An immunocytochemical and biochemical study.

Authors:  A O Jorgensen; L R Jones
Journal:  J Biol Chem       Date:  1986-03-15       Impact factor: 5.157

4.  Characterization of structural unit of phospholamban by amino acid sequencing and electrophoretic analysis.

Authors:  J Fujii; M Kadoma; M Tada; H Toda; F Sakiyama
Journal:  Biochem Biophys Res Commun       Date:  1986-08-14       Impact factor: 3.575

5.  Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle.

Authors:  C J Brandl; S deLeon; D R Martin; D H MacLennan
Journal:  J Biol Chem       Date:  1987-03-15       Impact factor: 5.157

6.  Phosphorylation and dephosphorylation of purified phospholamban and associated phosphatidylinositides.

Authors:  G Jakab; E G Kranias
Journal:  Biochemistry       Date:  1988-05-17       Impact factor: 3.162

7.  Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

Authors:  J Lytton; D H MacLennan
Journal:  J Biol Chem       Date:  1988-10-15       Impact factor: 5.157

8.  Deletion mapping of the inducible promoter of human IFN-beta gene.

Authors:  J Tavernier; D Gheysen; F Duerinck; J Van der Heyden; W Fiers
Journal:  Nature       Date:  1983 Feb 17-23       Impact factor: 49.962

9.  Proteolytic activation of the canine cardiac sarcoplasmic reticulum calcium pump.

Authors:  M A Kirchberger; D Borchman; C Kasinathan
Journal:  Biochemistry       Date:  1986-09-23       Impact factor: 3.162

10.  Immunoelectron microscopical localization of phospholamban in adult canine ventricular muscle.

Authors:  A O Jorgensen; L R Jones
Journal:  J Cell Biol       Date:  1987-05       Impact factor: 10.539
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  47 in total

1.  Transmembrane helix 11 is a genuine regulator of the endoplasmic reticulum Ca2+ pump and acts as a functional parallel of β-subunit on α-Na+,K+-ATPase.

Authors:  Przemek A Gorski; Catharine A Trieber; Els Larivière; Marleen Schuermans; Frank Wuytack; Howard S Young; Peter Vangheluwe
Journal:  J Biol Chem       Date:  2012-04-23       Impact factor: 5.157

2.  Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle.

Authors:  C M Misquitta; A Sing; A K Grover
Journal:  Biochem J       Date:  1999-02-15       Impact factor: 3.857

3.  Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase SERCA2a pump activity on cytosolic calcium in living cells.

Authors:  Kanayo Satoh; Toru Matsu-Ura; Masahiro Enomoto; Hideki Nakamura; Takayuki Michikawa; Katsuhiko Mikoshiba
Journal:  J Biol Chem       Date:  2011-04-22       Impact factor: 5.157

4.  Sarco/endoplasmic reticulum Ca2+-ATPase isoforms: diverse responses to acidosis.

Authors:  H Wolosker; J B Rocha; S Engelender; R Panizzutti; J De Miranda; L de Meis
Journal:  Biochem J       Date:  1997-01-15       Impact factor: 3.857

Review 5.  Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy.

Authors:  Changwon Kho; Ahyoung Lee; Roger J Hajjar
Journal:  Nat Rev Cardiol       Date:  2012-10-23       Impact factor: 32.419

6.  The Phospholamban Pentamer Alters Function of the Sarcoplasmic Reticulum Calcium Pump SERCA.

Authors:  John Paul Glaves; Joseph O Primeau; L Michel Espinoza-Fonseca; M Joanne Lemieux; Howard S Young
Journal:  Biophys J       Date:  2019-01-22       Impact factor: 4.033

7.  Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

Authors:  Larissa Lipskaia; Zela Keuylian; Karl Blirando; Nathalie Mougenot; Adeline Jacquet; Clotilde Rouxel; Haifa Sghairi; Ziane Elaib; Regis Blaise; Serge Adnot; Roger J Hajjar; Elie R Chemaly; Isabelle Limon; Regis Bobe
Journal:  Biochim Biophys Acta       Date:  2014-08-07

8.  Characterization of two different Ca2+ uptake and IP3-sensitive Ca2+ release mechanisms in microsomal Ca2+ pools of rat pancreatic acinar cells.

Authors:  T Ozawa; F Thévenod; I Schulz
Journal:  J Membr Biol       Date:  1995-03       Impact factor: 1.843

9.  Identification of functionally segregated sarcoplasmic reticulum calcium stores in pulmonary arterial smooth muscle.

Authors:  Jill H Clark; Nicholas P Kinnear; Svetlana Kalujnaia; Gordon Cramb; Sidney Fleischer; Loice H Jeyakumar; Frank Wuytack; A Mark Evans
Journal:  J Biol Chem       Date:  2010-02-21       Impact factor: 5.157

10.  Nonlinear gap junctions enable long-distance propagation of pulsating calcium waves in astrocyte networks.

Authors:  Mati Goldberg; Maurizio De Pittà; Vladislav Volman; Hugues Berry; Eshel Ben-Jacob
Journal:  PLoS Comput Biol       Date:  2010-08-26       Impact factor: 4.475
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