Literature DB >> 132683

Analgesic effect of fluoxetine hydrochloride (Lilly 110140), a specific inhibitor of serotonin uptake.

R B Messing, L Phebus, L A Fisher, L D Lytle.   

Abstract

Rats treated with Lilly 110140, a specific inhibitor of serotonin re-uptake in brain, are less sensitive to electroshock. Lilly 110140 antagonizes the hyperalgesia following injections of p-chlorophenylalanine and potentiates morphine analgesia. Naloxone blocks the analgesia following morphine, but has no effect on Lilly 110140-induced analgesia. Brain serotonin neurons may, at least in part, mediate analgesia.

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Year:  1975        PMID： 132683

Source DB:  PubMed          Journal:  Psychopharmacol Commun        ISSN： 0098-616X


  15 in total

1.  Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).

Authors:  Toru Kobayashi; Kazuo Washiyama; Kazutaka Ikeda
Journal:  Br J Pharmacol       Date:  2003-03       Impact factor: 8.739

2.  Differences in the effects of d-fenfluramine and morphine on various responses of rats to painful stimuli.

Authors:  C Rochat; L Cervo; S Romandini; R Samanin
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

3.  Fluoxetine enhances memory processing in mice.

Authors:  J F Flood; A Cherkin
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

4.  Chronic effects of fluoxetine, a selective inhibitor of serotonin uptake, on neurotransmitter receptors.

Authors:  D T Wong; L R Reid; F P Bymaster; P G Threlkeld
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

5.  Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms.

Authors:  Supriya Srinivasan; Leila Sadegh; Ida C Elle; Anne G L Christensen; Nils J Faergeman; Kaveh Ashrafi
Journal:  Cell Metab       Date:  2008-06       Impact factor: 27.287

6.  Attenuation of pethidine-induced antinociception by zimelidine, an inhibitor of 5-hydroxytryptamine reuptake.

Authors:  G F Gebhart; S A Lorens
Journal:  Br J Pharmacol       Date:  1980-11       Impact factor: 8.739

7.  Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia.

Authors:  S O Ogren; A C Holm
Journal:  J Neural Transm       Date:  1980       Impact factor: 3.575

8.  On the role of 5-hydroxytryptamine in drug-induced antinociception.

Authors:  M F Sugrue
Journal:  Br J Pharmacol       Date:  1979-04       Impact factor: 8.739

Review 9.  Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder.

Authors:  Nicholas T Bello; Bryn L Yeomans
Journal:  Expert Opin Drug Saf       Date:  2017-10-31       Impact factor: 4.250

Review 10.  Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.

Authors:  P Benfield; R C Heel; S P Lewis
Journal:  Drugs       Date:  1986-12       Impact factor: 9.546
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