| Literature DB >> 1325360 |
P Arvola1, I Pörsti, P Vuorinen, H Huhtala, T Metsä-Ketelä, H Vapaatalo.
Abstract
The effects of 1 mM L-cysteine on sodium nitrite-, 3-morpholinosydnonimine (SIN-1)- and acetylcholine-induced relaxation and cyclic GMP accumulation were studied in isolated noradrenaline-precontracted rat mesenteric arterial rings. L-Cysteine augmented the relaxation and cyclic GMP increase induced by sodium nitrate and SIN-1 but not those induced by acetylcholine. The effects of L-cysteine on relaxation were independent of the presence of intact endothelium. The results suggest that L-cysteine protects exogenously released nitric oxide.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1325360 DOI： 10.1016/0014-2999(92)90133-o
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432