Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Growth factors and cutaneous wound repair.

Literature DB >> 1325207

Growth factors and cutaneous wound repair.

P Martin¹, J Hopkinson-Woolley, J McCluskey.

Abstract

The healing of an adult skin lesion is a well studied but complex affair of some considerable clinical interest. Endogenous growth factors, including the EGF, FGF, PDGF and TGF beta families, are released at the wound site and presumed to be a necessary part of the natural wound healing machinery. Moreover, members of each of these families have been shown to enhance healing if added exogenously to a wound site. In this review we shall briefly discuss what is known about the mechanics and cell biology of adult wound healing, describe the normal cellular source of growth factors during the healing process and, with reference to their known capacities in tissue culture, speculate as to how particular growth factors might be able to enhance healing.

Entities: Disease Gene

Mesh：

Substances：

Year: 1992 PMID： 1325207 DOI： 10.1016/0955-2235(92)90003-z

Source DB: PubMed Journal: Prog Growth Factor Res ISSN： 0955-2235

Keyword Cloud
Cited

24 in total

9. Suppression of LPS-induced matrix-metalloproteinase responses in macrophages exposed to phenytoin and its metabolite, 5-(p-hydroxyphenyl-), 5-phenylhydantoin.

Authors: Ryan Serra; Abdel-Ghany Al-Saidi; Nikola Angelov; Salvador Nares
Journal: J Inflamm (Lond) Date: 2010-09-15 Impact factor: 4.981

10. Thrombospondin co-localises with TGF beta and IGF-I in the extracellular matrix of human osteoblast-like cells and is modulated by 17 beta estradiol.

Authors: M Slater; J Patava; R S Mason
Journal: Experientia Date: 1995-03-15

Growth factors and cutaneous wound repair.

1. A Predictive Tool for Foreign Body Fibrotic Reactions Using 2-Dimensional Computational Model.

2. Proliferation and tube formation of periodontal endothelial cells.

Review 3. Platelet-rich plasma and platelet gel: a review.

4. Stress-activated protein kinases are negatively regulated by cell density.

5. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

Review 6. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity.

7. The selection of peritoneal mesothelial cells is important for cell therapy to prevent peritoneal fibrosis.

8. Delayed fracture healing in tetranectin-deficient mice.

9. Suppression of LPS-induced matrix-metalloproteinase responses in macrophages exposed to phenytoin and its metabolite, 5-(p-hydroxyphenyl-), 5-phenylhydantoin.

10. Thrombospondin co-localises with TGF beta and IGF-I in the extracellular matrix of human osteoblast-like cells and is modulated by 17 beta estradiol.