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Literature DB >> 13242589

Effects of cortisone on rat liver mitochondria.

Abstract

Experiments were designed to determine the effects of parenteral administration of cortisone on mitochondrial numbers of rat liver cells. Observations were made in three ways: (1) after osmic acid fixation and appropriate stain, (2) by phase microscopy on intact cells, (3) by actual enumeration of mitochondria and nuclei to provide data on mitochondria per cell. The results of the experiments indicate that the mitochondria per cell are significantly reduced under the conditions used. Each experimental approach provided similar data, and each tended to support the results obtained from the others.

Entities: Chemical Species

Keywords: CORTISONE/effects; LIVER/effect of drugs on; MITOCHONDRIA

Mesh：

Substances：

Year: 1955 PMID： 13242589 PMCID： PMC2223815 DOI： 10.1083/jcb.1.3.237

Source DB: PubMed Journal: J Biophys Biochem Cytol ISSN： 0095-9901

14 in total

1. Rate of synthesis of desoxyribonucleic acid and mitotic rate in liver and intestine.

Authors: C E STEVENS; R DAOUST; C P LEBLOND
Journal: J Biol Chem Date: 1953-05 Impact factor: 5.157

2. The effects of cortisone upon the parenchymal cells of the rabbit liver.

Authors: W L WILLIAMS; C U LOWE; L THOMAS
Journal: Anat Rec Date: 1953-02

3. Quantitative morphological studies on the livers and liver homogenates of rats fed 2-methyl- or 3 -methyl-4-dimethylaminoazobenzene.

Authors: M J STRIEBICH; E SHELTON; W C SCHNEIDER
Journal: Cancer Res Date: 1953-03 Impact factor: 12.701

4. Enzymatic and chemical studies on the livers and liver mitochondria of rats fed 2-methyl- or 3-methyl-4-dimethylaminoazobenzene.

Authors: W C SCHNEIDER; G H HOGEBOOM; E SHELTON; M J STRIEBICH
Journal: Cancer Res Date: 1953-03 Impact factor: 12.701

9. Cellular changes in the chick chorio-allantoic membrane infected with herpes simplex and vaccinia; a study with thin sections for the electron microscope.

Authors: F B BANG
Journal: Bull Johns Hopkins Hosp Date: 1950-12

Effects of cortisone on rat liver mitochondria.

1. Rate of synthesis of desoxyribonucleic acid and mitotic rate in liver and intestine.

2. The effects of cortisone upon the parenchymal cells of the rabbit liver.

3. Quantitative morphological studies on the livers and liver homogenates of rats fed 2-methyl- or 3 -methyl-4-dimethylaminoazobenzene.

4. Enzymatic and chemical studies on the livers and liver mitochondria of rats fed 2-methyl- or 3-methyl-4-dimethylaminoazobenzene.

5. Effect of cortisone administration on intracellular composition of rat liver.

6. Cytoplasmic changes in hepatic parenchyma of mice during starvation and carbon tetrachloride-induced injury.

7. [Effect of cortisone on nucleic acid content of different tissue].

8. The measurement of proliferation in tissue cultures by enumeration of cell nuclei.

9. Cellular changes in the chick chorio-allantoic membrane infected with herpes simplex and vaccinia; a study with thin sections for the electron microscope.

10. Oxidation and phosphorylation in liver mitochondria lacking polymerized ribonucleic acid.

1. Electron microscopic study of the superior cervical ganglion.

2. Histochemical and electron microscopic study on steroid-induced ulcer in rat stomach.

3. Formation of enlarged mitochondria in a liver cell line in response to a synthetic glucocorticoid.

4. Effects of cortisone administration on rat liver mitochondria. Support for the concept of mitochondrial fusion.

5. A quantitative description of cortisone-induced alterations in the ultrastructure of rat liver parenchmal cells.

6. Cortisone-induced alterations in mitochondrial function and structure.

7. Sedimentation properties of rat liver mitochondria. Effects of cortisone treatment.