Literature DB >> 1324195

Antibody to the inositol trisphosphate receptor blocks thimerosal-enhanced Ca(2+)-induced Ca2+ release and Ca2+ oscillations in hamster eggs.

S Miyazaki1, H Shirakawa, K Nakada, Y Honda, M Yuzaki, S Nakade, K Mikoshiba.   

Abstract

The sulfhydryl reagent thimerosal enhanced the sensitivity of hamster eggs to injected inositol 1,4,5-trisphosphate (InsP3) or Ca2+ to generate regenerative Ca2+ release from intracellular pools. A monoclonal antibody (mAb) to the InsP3 receptor blocked both the InsP3-induced Ca2+ release (IICR) and Ca(2+)-induced Ca2+ release (CICR). The mAb also blocked Ca2+ oscillations induced by thimerosal. The results indicate that thimerosal enhances IICR sensitized by cytosolic Ca2+, but not CICR from InsP3-insensitive pools, and causes repetitive Ca2+ releases from InsP3-sensitive pools.

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Year:  1992        PMID： 1324195     DOI： 10.1016/0014-5793(92)81090-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  15 in total

1.  Distinct temporal profiles of activity-dependent calcium increase in pyramidal neurons of the rat visual cortex.

Authors:  N Kato; T Tanaka; K Yamamoto; Y Isomura
Journal:  J Physiol       Date:  1999-09-01       Impact factor: 5.182

2.  Effects of thimerosal on the transient kinetics of inositol 1,4,5-trisphosphate-induced Ca2+ release from cerebellar microsomes.

Authors:  M Mezna; F Michelangeli
Journal:  Biochem J       Date:  1997-07-01       Impact factor: 3.857

Review 3.  Sperm contributions to oocyte activation: more that meets the eye.

Authors:  George Anifandis; Christina I Messini; Konstantinos Dafopoulos; Alexandros Daponte; Ioannis E Messinis
Journal:  J Assist Reprod Genet       Date:  2016-01-16       Impact factor: 3.412

4.  Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling.

Authors:  Annabelle Méry; Franck Aimond; Claudine Ménard; Katsuhiko Mikoshiba; Marek Michalak; Michel Pucéat
Journal:  Mol Biol Cell       Date:  2005-03-09       Impact factor: 4.138

Review 5.  Inositol trisphosphate receptor Ca2+ release channels.

Authors:  J Kevin Foskett; Carl White; King-Ho Cheung; Don-On Daniel Mak
Journal:  Physiol Rev       Date:  2007-04       Impact factor: 37.312

6.  Contributions of extracellular and intracellular Ca2+ to regulation of sperm motility: Release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm.

Authors:  Becky Marquez; George Ignotz; Susan S Suarez
Journal:  Dev Biol       Date:  2006-11-10       Impact factor: 3.582

7.  Relationship between latency and period for 5-hydroxytryptamine-induced membrane responses in the Calliphora salivary gland.

Authors:  M J Berridge
Journal:  Biochem J       Date:  1994-09-01       Impact factor: 3.857

8.  The inositol 1,4,5-trisphosphate-gated Ca2+ channel: effect of the protein thiol reagent thimerosal on channel activity.

Authors:  E C Thrower; H Duclohier; E J Lea; G Molle; A P Dawson
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

9.  Bell-shaped activation of inositol-1,4,5-trisphosphate-induced Ca2+ release by thimerosal in permeabilized A7r5 smooth-muscle cells.

Authors:  J B Parys; L Missiaen; H De Smedt; G Droogmans; R Casteels
Journal:  Pflugers Arch       Date:  1993-09       Impact factor: 3.657

10.  Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction.

Authors:  Geert Bultynck; Karolina Szlufcik; Nael Nadif Kasri; Zerihun Assefa; Geert Callewaert; Ludwig Missiaen; Jan B Parys; Humbert De Smedt
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857
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