Literature DB >> 13233455

The antigenic potency of non-infectious poliomyelitis virus as determined by its liberating effect on active virus neutralized by immune serum.

U KRECH.   

Abstract

The activation of poliomyelitis virus from a "neutral" virus-antibody mixture by the addition of non-infectious virus is described. The phenomenon was demonstrated in tissue cultures using both Petri dishes and roller tubes. The reaction was found to be type-specific and a relationship between antigen dilution and number of plaques counted was established. The relative potency of vaccine preparations determined in this system was found to be comparable to their relative potency in respect to protection-inducing activity in mice.

Entities:  

Keywords:  ANTIGENS AND ANTIBODIES; POLIOMYELITIS VIRUS

Mesh:

Substances:

Year:  1955        PMID: 13233455      PMCID: PMC2136467          DOI: 10.1084/jem.101.3.331

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  8 in total

1.  Studies in human subjects on active immunization against poliomyelitis. II. A practical means for inducing and maintaining antibody formation.

Authors:  J E SALK; P L BAZELEY; B L BENNETT; U KRECH; L J LEWIS; E N WARD; J S YOUNGNER
Journal:  Am J Public Health Nations Health       Date:  1954-08

2.  Preparation and standardization of antiserums prepared with the three known types to poliomyelitis viruses.

Authors:  H A WENNER; C A MILLER; P KAMITSUKA; J C WILSON
Journal:  Am J Hyg       Date:  1954-03

3.  Formaldehyde treatment and safety testing of experimental poliomyelitis vaccines.

Authors:  J E SALK; U KRECH; J S YOUNGNER; B L BENNETT; L J LEWIS; P L BAZELEY
Journal:  Am J Public Health Nations Health       Date:  1954-05

4.  Antibody response of chimpanzees and human beings to formalin-inactivated trivalent poliomyelitis vaccine.

Authors:  H A HOWE
Journal:  Am J Hyg       Date:  1952-11

5.  Immunization of mice with inactivated type 2 poliomyelitis virus against types 2 and 3 viruses.

Authors:  J CASALS; P K OLITSKY; L V BROWN
Journal:  Proc Soc Exp Biol Med       Date:  1952 Aug-Sep

6.  The use of adjuvants to facilitate studies on the immunologic classification of poliomyelitis viruses.

Authors:  J E SALK; L J LEWIS; J S YOUNGNER; B L BENNETT
Journal:  Am J Hyg       Date:  1951-09

7.  Immunization of cotton rats with inactivated Lansing poliomyelitis virus. I. Inactivation by chemical agents.

Authors:  C E SCHWERDT; G W A DICK; R M HERRIOTT; H A HOWE
Journal:  Am J Hyg       Date:  1951-03

8.  Plaque formation and isolation of pure lines with poliomyelitis viruses.

Authors:  R DULBECCO; M VOGT
Journal:  J Exp Med       Date:  1954-02       Impact factor: 14.307

  8 in total
  6 in total

1.  Potency of poliomyelitis vaccines estimated by an antibody combining test.

Authors:  J G CRAWFORD; M F FIELD
Journal:  J Bacteriol       Date:  1960-07       Impact factor: 3.490

2.  [Determination of the antigenic value of poliomyelitis vaccine].

Authors:  P DE SOMER; A PRINZIE; E DE MAEYER; M LAMY
Journal:  Bull World Health Organ       Date:  1960       Impact factor: 9.408

3.  Neutralizing-antibody-combining (NAC) test for measuring antigenic potency of poliomyelitis vaccine.

Authors:  M BENYESH-MELNICK; J L MELNICK
Journal:  Bull World Health Organ       Date:  1959       Impact factor: 9.408

4.  The determination of antigenic potency of poliomyelitis vaccine by measuring its antibody-combining capacity.

Authors:  U KRECH
Journal:  Bull World Health Organ       Date:  1960       Impact factor: 9.408

5.  [The kinetic reaction of sero-neutralization of poliomyelitis virus].

Authors:  P LEPINE; F ROGER; A ROGER
Journal:  Bull World Health Organ       Date:  1959       Impact factor: 9.408

6.  Detection of respiratory syncytial virus in nasopharyngeal secretions by inhibition of enzyme-linked immunosorbent assay.

Authors:  A Hornsleth; E Brenøe; B Friis; F U Knudsen; P Uldall
Journal:  J Clin Microbiol       Date:  1981-11       Impact factor: 5.948

  6 in total

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