| Literature DB >> 1321789 |
A A Armstrong1, A Gallagher, A S Krajewski, D B Jones, B S Wilkins, D E Onions, R F Jarrett.
Abstract
A series of 33 cases of Hodgkin's disease was investigated for the presence of the EBV encoded latent gene product LMP-1 and of CD23 using immunohistochemical techniques. The expression of bcl-2 was examined in a subset of cases. LMP-1 was detected in the Reed-Sternberg cells in 15 cases. Although LMP-1 is known to upregulate CD23 and bcl-2, there was no correlation between the expression of LMP-1 and the detection of CD23 and bcl-2 in Reed-Sternberg cells.Entities:
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Year: 1992 PMID: 1321789 DOI: 10.1111/j.1365-2559.1992.tb00346.x
Source DB: PubMed Journal: Histopathology ISSN: 0309-0167 Impact factor: 5.087