| Literature DB >> 1321676 |
H Oguchi1, K Ishikawa, S Ojima, Y Hirayama, K Seto, G Eguchi.
Abstract
Titanium alloy sprayed with hydroxyapatite (HA) was developed by a high-velocity flame-spraying technique (HVFST). Biocompatible responses of bony tissues to high-velocity flame-sprayed HA (HVFS-HA) implanted into tibias of adult male rabbits was investigated 4 and 18 months after implantation by light and electron microscopy. Both light and electron microscope features in histological sections showed that inflammatory responses of tissues in situ were completely cleared and the interface between the bone and the implant was filled with newly formed bony substrate. This suggests that the HVFS-HA was sufficiently biocompatible to be adapted to the bone in situ.Entities:
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Year: 1992 PMID： 1321676 DOI： 10.1016/0142-9612(92)90169-o
Source DB: PubMed Journal: Biomaterials ISSN： 0142-9612 Impact factor: 12.479