Literature DB >> 1321352

Immunocytochemical localization of ubiquitin at human neuromuscular junctions.

P Serdaroglu1, V Askanas, W K Engel.   

Abstract

Using several specific monoclonal and polyclonal antibodies, we found that ubiquitin is highly concentrated in the post-synaptic domain of human neuromuscular junctions. The distribution and pattern of ubiquitin immunoreactivity is identical to the localization of bound alpha-bungarotoxin, suggesting that ubiquitin may be involved in post-translational modification or turnover of the acetylcholine receptor or other junctional proteins of the muscle fibre.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1321352     DOI: 10.1111/j.1365-2990.1992.tb00785.x

Source DB:  PubMed          Journal:  Neuropathol Appl Neurobiol        ISSN: 0305-1846            Impact factor:   8.090


  6 in total

Review 1.  Ubiquitination in postsynaptic function and plasticity.

Authors:  Angela M Mabb; Michael D Ehlers
Journal:  Annu Rev Cell Dev Biol       Date:  2010       Impact factor: 13.827

2.  Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau.

Authors:  V Askanas; W K Engel; M Bilak; R B Alvarez; D J Selkoe
Journal:  Am J Pathol       Date:  1994-01       Impact factor: 4.307

3.  Strong immunoreactivity of alpha 1-antichymotrypsin co-localizes with beta-amyloid protein and ubiquitin in vacuolated muscle fibers of inclusion-body myositis.

Authors:  M Bilak; V Askanas; W K Engel
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

4.  Vezatin is required for the maturation of the neuromuscular synapse.

Authors:  Natasha Koppel; Matthew B Friese; Helene L Cardasis; Thomas A Neubert; Steven J Burden
Journal:  Mol Biol Cell       Date:  2019-08-14       Impact factor: 4.138

5.  Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice.

Authors:  Yun Liu; Hongqiao Li; Yoshie Sugiura; Weiping Han; Gilbert Gallardo; Mikhail Khvotchev; Yinan Zhang; Ege T Kavalali; Thomas C Südhof; Weichun Lin
Journal:  J Neurosci       Date:  2015-08-19       Impact factor: 6.167

6.  Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction.

Authors:  Zhonghua Lu; Hyun-Soo Je; Paul Young; Jimmy Gross; Bai Lu; Guoping Feng
Journal:  J Cell Biol       Date:  2007-06-18       Impact factor: 10.539

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.