Literature DB >> 132133

The social effect of Huntington's chorea on reproductive effectiveness.

D C Wallace.   

Abstract

An attempt has been made to account for the observed departures from a model of a simple single-locus inheritance in Huntington's Chorea. It is postulated that an indirect effect of the abnormal allele lies in its social effects on individuals in the family group whether they bear the allele or not. This acts by influencing their mate-finding and reproductive behaviour so as to produce the observed statistical anomalies.

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Year:  1976        PMID： 132133     DOI： 10.1111/j.1469-1809.1976.tb00142.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN： 0003-4800            Impact factor:   1.670


  6 in total

Review 1.  Sexuality in Huntington's disease.

Authors:  Eva Z Schmidt; Raphael M Bonelli
Journal:  Wien Med Wochenschr       Date:  2008

2.  Theories of social selection in human populations.

Authors:  S Yokoyama
Journal:  Am J Hum Genet       Date:  1983-05       Impact factor: 11.025

3.  The mutation rate to Huntington's chorea.

Authors:  M Shaw; A Caro
Journal:  J Med Genet       Date:  1982-06       Impact factor: 6.318

4.  Social selection in human populations: fitness modification of offspring by an affected parent at two loci.

Authors:  S Yokoyama
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

Review 5.  Huntington disease: genetics and epidemiology.

Authors:  P M Conneally
Journal:  Am J Hum Genet       Date:  1984-05       Impact factor: 11.025

6.  Two models for a maternal factor in the inheritance of Huntington disease.

Authors:  M Boehnke; P M Conneally; K Lange
Journal:  Am J Hum Genet       Date:  1983-09       Impact factor: 11.025
  6 in total

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