Literature DB >> 1321073

Aluminum(III) facilitates the oxidation of NADH by the superoxide anion.

S Kong1, S Liochev, I Fridovich.   

Abstract

Al(III) augments the oxidation of reduced nicotinamide adenine dinucleotide (NADH) by enzymatic or photochemical sources of O2-. Superoxide dismutase, but not catalase, inhibited this action of Al(III). It thus appears that Al(III) forms a complex with O2-, which is a stronger oxidant than is O2- itself and which may contribute to the adverse biological effects of Al(III).

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Year:  1992        PMID: 1321073     DOI: 10.1016/0891-5849(92)90168-g

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN: 0891-5849            Impact factor:   7.376


  12 in total

1.  Synergistic effect of aluminum and ionizing radiation upon ultrastructure, oxidative stress and apoptotic alterations in Paneth cells of rat intestine.

Authors:  N A Eltahawy; S M Elsonbaty; S Abunour; W E Zahran
Journal:  Environ Sci Pollut Res Int       Date:  2017-01-12       Impact factor: 4.223

2.  Nanoparticle and iron chelators as a potential novel Alzheimer therapy.

Authors:  Gang Liu; Ping Men; George Perry; Mark A Smith
Journal:  Methods Mol Biol       Date:  2010

Review 3.  Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts.

Authors:  Calvin C Willhite; Nataliya A Karyakina; Robert A Yokel; Nagarajkumar Yenugadhati; Thomas M Wisniewski; Ian M F Arnold; Franco Momoli; Daniel Krewski
Journal:  Crit Rev Toxicol       Date:  2014-10       Impact factor: 5.635

4.  Reversal of an aluminium induced alteration in redox status in different regions of rat brain by administration of centrophenoxine.

Authors:  Bimla Nehru; Punita Bhalla
Journal:  Mol Cell Biochem       Date:  2006-09-13       Impact factor: 3.396

5.  Aluminum enhances melanin-induced lipid peroxidation.

Authors:  L Meglio; P I Oteiza
Journal:  Neurochem Res       Date:  1999-08       Impact factor: 3.996

Review 6.  Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!

Authors:  David J Bonda; Gang Liu; Ping Men; George Perry; Mark A Smith; Xiongwei Zhu
Journal:  CNS Neurol Disord Drug Targets       Date:  2012-02       Impact factor: 4.388

7.  Protective role of lithium in ameliorating the aluminium-induced oxidative stress and histological changes in rat brain.

Authors:  Punita Bhalla; D K Dhawan
Journal:  Cell Mol Neurobiol       Date:  2009-01-29       Impact factor: 5.046

8.  Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease.

Authors:  Gang Liu; Ping Men; George Perry; Mark A Smith
Journal:  J Nanoneurosci       Date:  2009-06-01

9.  Aluminium administration is associated with enhanced hepatic oxidant stress that may be offset by dietary vitamin E in the rat.

Authors:  M G Abubakar; A Taylor; G A A Ferns
Journal:  Int J Exp Pathol       Date:  2003-02       Impact factor: 1.925

10.  Antioxidant enzymatic system in neuronal and glial cells enriched fractions of rat brain after aluminum exposure.

Authors:  Pooja Khanna; Bimla Nehru
Journal:  Cell Mol Neurobiol       Date:  2007-11-28       Impact factor: 5.046

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