Literature DB >> 1320521

First seizure in adults: to treat or not to treat.

B Chandra1.   

Abstract

A double-blind trial was done in 228 patients with one single seizure 2 weeks before coming to the author. One group was given sodium valproate, the other group placebo. The duration of therapy was 12 months. The results of this trial show that a person with a single seizure has epilepsy and should be treated with sodium valproate.

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Year:  1992        PMID： 1320521     DOI： 10.1016/0303-8467(92)90024-w

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN： 0303-8467            Impact factor:   1.876


  9 in total

1.  Evidence-Based Guideline: Management of an Unprovoked First Seizure in Adults: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Authors:  A Krumholz; S Wiebe; G S Gronseth; D S Gloss; A M Sanchez; A A Kabir; A T Liferidge; J P Martello; A M Kanner; S Shinnar; J L Hopp; J A French
Journal:  Epilepsy Curr       Date:  2015 May-Jun       Impact factor: 7.500

2.  Evidence-based guideline: Management of an unprovoked first seizure in adults: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Authors:  Allan Krumholz; Samuel Wiebe; Gary S Gronseth; David S Gloss; Ana M Sanchez; Arif A Kabir; Aisha T Liferidge; Justin P Martello; Andres M Kanner; Shlomo Shinnar; Jennifer L Hopp; Jacqueline A French
Journal:  Neurology       Date:  2015-04-21       Impact factor: 9.910

Review 3.  Managing an Unprovoked First Seizure in Adults.

Authors:  David S Gloss; Allan Krumholz
Journal:  CNS Drugs       Date:  2016-03       Impact factor: 5.749

Review 4.  Do anticonvulsants alter the natural course of epilepsy? Treatment should be started as early as possible.

Authors:  E H Reynolds
Journal:  BMJ       Date:  1995-01-21

Review 5.  Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.

Authors:  Maurizio A Leone; Giorgia Giussani; Sarah J Nolan; Anthony G Marson; Ettore Beghi
Journal:  Cochrane Database Syst Rev       Date:  2016-05-06

Review 6.  Epilepsy (partial).

Authors:  Melissa Maguire; Anthony G Marson; Sridharan Ramaratnam
Journal:  BMJ Clin Evid       Date:  2011-05-06

7.  Management of provoked seizure.

Authors:  Usha Kant Misra; Jayantee Kalita
Journal:  Ann Indian Acad Neurol       Date:  2011-01       Impact factor: 1.383

8.  Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.

Authors:  Maurizio A Leone; Giorgia Giussani; Sarah J Nevitt; Anthony G Marson; Ettore Beghi
Journal:  Cochrane Database Syst Rev       Date:  2021-05-04

9.  Antiepileptic drug treatment after an unprovoked first seizure: A decision analysis.

Authors:  Erik L Bao; Ling-Ya Chao; Peiyun Ni; Lidia M V R Moura; Andrew J Cole; Sydney S Cash; Daniel B Hoch; Matt T Bianchi; M Brandon Westover
Journal:  Neurology       Date:  2018-09-12       Impact factor: 11.800
  9 in total

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