Determining the prognosis of childhood epilepsies by establishing immune abnormalities.

When seizures develop in a child, an accurate prediction on outcome of the disorder can hardly be given. Literature indicating an association between seizure disorders and Immunoglobulin (Ig) abnormalities, HLA typing and the occurrence of anti-brain antibodies is shortly reviewed. It is argued that by determining such anti-brain antibodies, early ascertainment of prognosis in seizure disorders may be possible.