Literature DB >> 132034

Carcinogenic effects of different nitroso-compounds in Chinese hamsters. II. N-nitrosomorpholine and N-nitrosopiperidine.

G Reznik, U Mohr, N Kmoch.   

Abstract

A total of 320 Chinese hamsters (Cricetulus griseus) (CH) were subcutaneously (s.c.) treated with 1/5, 1/10, or 1/20 LD50 of N-nitrosomorpholine (NM) or N-nitrosopiperidine (NP). In the CH, NM and NP both produced up to a 100% rate of papillomas of the cheek pouch, tongue, pharynx, esophagus and forestomach. Occasionally squamous cell carcinomas also developed in these organs. A high rate of hepatomas was realized by NP.

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Year:  1976        PMID： 132034     DOI： 10.1007/bf00304939

Source DB:  PubMed          Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol        ISSN： 0084-5353


  3 in total

1.  Comparative studies with different doses of N-nitrosomorpholine, N-nitrosopiperidine, N-nitrosomethylurea, and dimethylnitrosamine in Syrian golden hamsters.

Authors:  H Haas; U Mohr; F W Krüger
Journal:  J Natl Cancer Inst       Date:  1973-10       Impact factor: 13.506

2.  Carcinogenic effects of N-nitrosomorpholine and N-nitrosopiperidine on European hamster (Cricetus cricetus).

Authors:  U Mohr; G Reznik; H Reznik-Schüller
Journal:  J Natl Cancer Inst       Date:  1974-07       Impact factor: 13.506

3.  Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine.

Authors:  G Reznik; U Mohr; N Kmoch
Journal:  Br J Cancer       Date:  1976-04       Impact factor: 7.640
  3 in total
  1 in total

1.  [Neoplastic and preneoplastic lesions in rats after oral administration of a single dose of N-nitrosomorpholine (author's transl)].

Authors:  P Bannasch; D Mayer; R Krech
Journal:  J Cancer Res Clin Oncol       Date:  1979-07-27       Impact factor: 4.553
  1 in total

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