Literature DB >> 1320290

Expression of a ryanodine receptor-Ca2+ channel that is regulated by TGF-beta.

G Giannini1, E Clementi, R Ceci, G Marziali, V Sorrentino.   

Abstract

Ryanodine receptors (RyRs) are intracellular channels that release calcium ions from the sarcoplasmic reticulum (SR) in response to either plasma membrane depolarization (in skeletal muscle) or increases in the concentration of intracellular free Ca2+ (in the heart). A gene (beta 4) encoding a ryanodine receptor (similar to, but distinct from, the muscle RyRs) was identified. The beta 4 gene was expressed in all tissues investigated, with the exception of heart. Treatment of mink lung epithelial cells (Mv1Lu) with transforming growth factor beta (TGF-beta) induced expression of the beta 4 gene together with the release of Ca2+ in response to ryanodine (but not in response to caffeine, the other drug active on muscle RyRs). This ryanodine receptor may be important in the regulation of intracellular Ca2+ homeostasis.

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Year:  1992        PMID： 1320290     DOI： 10.1126/science.1320290

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  47 in total

1.  Identification and function of ryanodine receptor subtype 3 in non-pregnant mouse myometrial cells.

Authors:  J Mironneau; N Macrez; J L Morel; V Sorrentino; C Mironneau
Journal:  J Physiol       Date:  2002-02-01       Impact factor: 5.182

2.  Functional SNP in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification.

Authors:  Lina Zhang; Yuexin Liu; Fengju Song; Hong Zheng; Limei Hu; Hong Lu; Peifang Liu; Xishan Hao; Wei Zhang; Kexin Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-02       Impact factor: 11.205

3.  Proceedings of the scientific meetings of the Physiology Society. November 1996 and January 1997. Abstracts.

Authors: 
Journal:  J Physiol       Date:  1997-02       Impact factor: 5.182

4.  RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS).

Authors:  Aditi Shendre; Marguerite R Irvin; Bradley E Aouizerat; Howard W Wiener; Ana I Vazquez; Kathryn Anastos; Jason Lazar; Chenglong Liu; Roksana Karim; Nita A Limdi; Mardge H Cohen; Elizabeth T Golub; Degui Zhi; Robert C Kaplan; Sadeep Shrestha
Journal:  Atherosclerosis       Date:  2014-01-30       Impact factor: 5.162

Review 5.  Comparison of properties of Ca2+ release channels between rabbit and frog skeletal muscles.

Authors:  Y Ogawa; T Murayama; N Kurebayashi
Journal:  Mol Cell Biochem       Date:  1999-01       Impact factor: 3.396

6.  Pharmacological activation of the ryanodine receptor in Jurkat T-lymphocytes.

Authors:  M Hohenegger; I Berg; L Weigl; G W Mayr; B V Potter; A H Guse
Journal:  Br J Pharmacol       Date:  1999-11       Impact factor: 8.739

7.  Local control model of excitation-contraction coupling in skeletal muscle.

Authors:  M D Stern; G Pizarro; E Ríos
Journal:  J Gen Physiol       Date:  1997-10       Impact factor: 4.086

8.  Effects of caffeine on cytoplasmic free Ca2+ concentration in pancreatic beta-cells are mediated by interaction with ATP-sensitive K+ channels and L-type voltage-gated Ca2+ channels but not the ryanodine receptor.

Authors:  M S Islam; O Larsson; T Nilsson; P O Berggren
Journal:  Biochem J       Date:  1995-03-15       Impact factor: 3.857

9.  The time course of intracellular calcium movements in single human umbilical vein smooth muscle cells.

Authors:  J A Nicholls; J I Gillespie; J R Greenwell
Journal:  Pflugers Arch       Date:  1993-11       Impact factor: 3.657

10.  Inhibition of inositol trisphosphate-induced calcium release by caffeine is prevented by ATP.

Authors:  L Missiaen; J B Parys; H De Smedt; B Himpens; R Casteels
Journal:  Biochem J       Date:  1994-05-15       Impact factor: 3.857
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