Literature DB >> 1320

Fluorescence of oxidized flavoproteins from perifused isolated pancreatic islets.

U Panten, H Ishida.   

Abstract

In perifused pancreatic islets, the fluorescence of oxidized flavoproteins (FAD) was recorded continuously. Elevation of glucose concentration in the medium form 0 or 5 mM to 20 mM led to decrease in FAD-fluorescence beginning 10 sec after change of medium. L-leucine (10 mM), (+/-)-B-BCH (20 mM) and alpha-ketoisocaproic acid (10 mM) caused typical kinetics of FAD-fluorescence decrease. The results are interpreted to indicate rapid changes of the functional state of B-cell mitochondria induced by the above-mentioned stimulators of insulin release.

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Year:  1975        PMID： 1320     DOI： 10.1007/BF01222108

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  20 in total

1.  Effects of L-leucine and alpha-ketoisocaproic acid upon insulin secretion and metabolism of isolated pancreatic islets.

Authors:  U Panten; E v. Kriegstein; W Poser; J Schönborn; A Hasselblatt
Journal:  FEBS Lett       Date:  1972-02-01       Impact factor: 4.124

2.  An in vitro study of the interaction of heart mitochondria with troponin-bound Ca2+.

Authors:  E Carafoli; R Dabrowska; F Crovetti; R Tiozzo; W Drabikowski
Journal:  Biochem Biophys Res Commun       Date:  1975-02-17       Impact factor: 3.575

3.  A METHOD FOR THE MICRODISSECTION OF INTACT PANCREATIC ISLETS OF MAMMALS.

Authors:  C HELLERSTROEM
Journal:  Acta Endocrinol (Copenh)       Date:  1964-01

4.  Kinetics of mitochondrial flavoprotein and pyridine nucleotide in perfused heart.

Authors:  B Chance; I A Salkovitz; A G Kovach
Journal:  Am J Physiol       Date:  1972-07

5.  Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins.

Authors:  R Scholz; R G Thurman; J R Williamson; B Chance; T Bücher
Journal:  J Biol Chem       Date:  1969-05-10       Impact factor: 5.157

6.  Factors that influence phosphoenolpyruvate-induced calcium efflux from rat liver mitochondria.

Authors:  C F Peng; D W Price; C Bhuvaneswaran; C L Wadkins
Journal:  Biochem Biophys Res Commun       Date:  1974-01       Impact factor: 3.575

7.  [A method for superfusion of tissue samples for fluorescence measurements].

Authors:  U Panten; H Dal Ri; W Poser; A Hasselblatt
Journal:  Pflugers Arch       Date:  1971       Impact factor: 3.657

8.  Studies of a simplified plasma insulin immunoassaay using cellulose powder.

Authors:  D S Zaharko; L V Beck
Journal:  Diabetes       Date:  1968-07       Impact factor: 9.461

9.  Studies on the mechanism of L-leucine-and alpha-ketoisocaproic acid-induced insulin release from perifused isolated pancreatic islets.

Authors:  U Panten; J Christians; E von Kriegstein; W Poser; A Hasselblatt
Journal:  Diabetologia       Date:  1974-04       Impact factor: 10.122

10.  On the control of glycogenolysis in mammalian nervous tissue by calcium.

Authors:  D Landowne; J M Ritchie
Journal:  J Physiol       Date:  1971-01       Impact factor: 5.182
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  8 in total

1.  Different responses of mouse islets and MIN6 pseudo-islets to metabolic stimulation: a note of caution.

Authors:  Torben Schulze; Mai Morsi; Dennis Brüning; Kirstin Schumacher; Ingo Rustenbeck
Journal:  Endocrine       Date:  2015-07-31       Impact factor: 3.633

2.  Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets.

Authors:  U Panten
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

Review 3.  The biosociology of pancreatic B cells.

Authors:  D Pipeleers
Journal:  Diabetologia       Date:  1987-05       Impact factor: 10.122

Review 4.  Coupling factors in nutrient-induced insulin release.

Authors:  W J Malaisse; F Malaisse-Lagae; A Sener
Journal:  Experientia       Date:  1984-10-15

5.  Hexose metabolism in pancreatic islets: effect of D-glucose on the mitochondrial redox state.

Authors:  R Ramirez; A Sener; W J Malaisse
Journal:  Mol Cell Biochem       Date:  1995-01-12       Impact factor: 3.396

6.  Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic beta-cells.

Authors:  M R Duchen; P A Smith; F M Ashcroft
Journal:  Biochem J       Date:  1993-08-15       Impact factor: 3.857

7.  Single islet beta-cell stimulation by nutrients: relationship between pyridine nucleotides, cytosolic Ca2+ and secretion.

Authors:  W F Pralong; C Bartley; C B Wollheim
Journal:  EMBO J       Date:  1990-01       Impact factor: 11.598

Review 8.  What Is the Metabolic Amplification of Insulin Secretion and Is It (Still) Relevant?

Authors:  Ingo Rustenbeck; Torben Schulze; Mai Morsi; Mohammed Alshafei; Uwe Panten
Journal:  Metabolites       Date:  2021-06-02
  8 in total

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