Literature DB >> 1319984

Impaired long-term T cell immunity to Epstein-Barr virus in patients with nasopharyngeal carcinoma.

S Tamura1, A Yamazaki, M Kunimoto, K Takemura, T Tabata, Y Hinuma, O Yoshie.   

Abstract

The long-term T cell immunity to Epstein-Barr virus (EBV) is considered to play an important role in suppressing proliferation of EBV-infected B cells and outgrowth of EBV-associated tumors. It can be manifested and quantified by the EBV-induced focus regression assay. In the present study, we examined the strength of T cell immunity to EBV in patients with nasopharyngeal carcinoma (NPC) and other cancers originating from the head and neck region. In contrast to patients with other types of cancers, including EBV-negative NPC, patients with EBV-positive NPC were found to have a profound impairment in the long-term T cell immunity to EBV.

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Year:  1992        PMID： 1319984      PMCID： PMC5918858          DOI： 10.1111/j.1349-7006.1992.tb01948.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  35 in total

1.  Expression of the Epstein-Barr virus BamHI A fragment in nasopharyngeal carcinoma: evidence for a viral protein expressed in vivo.

Authors:  K J Gilligan; P Rajadurai; J C Lin; P Busson; M Abdel-Hamid; U Prasad; T Tursz; N Raab-Traub
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

2.  Generation of specific cytotoxic T cells with a fragment of the Epstein-Barr virus-encoded p63/latent membrane protein.

Authors:  D A Thorley-Lawson; E S Israelsohn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

3.  Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt lymphoma lines.

Authors:  M G Masucci; S Torsteindottir; J Colombani; C Brautbar; E Klein; G Klein
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

4.  Natural killer cells inhibit outgrowth of autologous Epstein-Barr virus-infected B lymphocytes.

Authors:  J Kaplan; T C Shope
Journal:  Nat Immun Cell Growth Regul       Date:  1985

5.  T-cell control of Epstein-Barr virus-infected B cells is lost during P. falciparum malaria.

Authors:  H C Whittle; J Brown; K Marsh; B M Greenwood; P Seidelin; H Tighe; L Wedderburn
Journal:  Nature       Date:  1984 Nov 29-Dec 5       Impact factor: 49.962

6.  In vitro analysis of the Epstein-Barr virus: host balance in long-term renal allograft recipients.

Authors:  Q Y Yao; A B Rickinson; J S Gaston; M A Epstein
Journal:  Int J Cancer       Date:  1985-01-15       Impact factor: 7.396

7.  Defective regulation of Epstein-Barr virus infection in patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related disorders.

Authors:  D L Birx; R R Redfield; G Tosato
Journal:  N Engl J Med       Date:  1986-04-03       Impact factor: 91.245

Review 8.  Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers.

Authors:  H zur Hausen
Journal:  Cancer Res       Date:  1989-09-01       Impact factor: 12.701

Review 9.  Immune surveillance against virus-induced tumors and nonrejectability of spontaneous tumors: contrasting consequences of host versus tumor evolution.

Authors:  G Klein; E Klein
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

10.  Restricted expression of EBV latent genes and T-lymphocyte-detected membrane antigen in Burkitt's lymphoma cells.

Authors:  D T Rowe; M Rowe; G I Evan; L E Wallace; P J Farrell; A B Rickinson
Journal:  EMBO J       Date:  1986-10       Impact factor: 11.598
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  1 in total

1.  Dendritic cells initiate immune control of epstein-barr virus transformation of B lymphocytes in vitro.

Authors:  Kara Bickham; Kiera Goodman; Casper Paludan; Sarah Nikiforow; Ming Li Tsang; Ralph M Steinman; Christian Münz
Journal:  J Exp Med       Date:  2003-12-01       Impact factor: 14.307
  1 in total

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