Literature DB >> 1319964

Leukotriene B4 in the immune system.

H E Claesson1, B Odlander, P J Jakobsson.   

Abstract

Leukotriene (LT) B4 is a biologically active molecule derived from arachidonic acid via the 5-lipoxygenase pathway. It mediates certain inflammatory and immunological reactions. The role of LTB4 in the immune system has been questioned since lymphocytes have been regarded to lack the enzymes involved in LTB4 formation. This review focuses on the recently described biosynthesis of LTB4 in B-lymphocytes and the effects of this compound on lymphocyte functions.

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Year:  1992        PMID： 1319964     DOI： 10.1016/0192-0561(92)90174-j

Source DB:  PubMed          Journal:  Int J Immunopharmacol        ISSN： 0192-0561


  17 in total

1.  The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis.

Authors:  Neelam Sharma-Walia; Karthic Chandran; Kinjan Patel; Mohanan Valiya Veettil; Alexandru Marginean
Journal:  J Virol       Date:  2013-12-11       Impact factor: 5.103

Review 2.  Long-chain polyunsaturated fatty acids and eicosanoids in infants--physiological and pathophysiological aspects and open questions.

Authors:  A Sellmayer; B Koletzko
Journal:  Lipids       Date:  1999-02       Impact factor: 1.880

3.  Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.

Authors:  D J Evans; P J Barnes; S M Spaethe; E L van Alstyne; M I Mitchell; B J O'Connor
Journal:  Thorax       Date:  1996-12       Impact factor: 9.139

4.  Exhaled breath condensate eicosanoid levels associate with asthma and its severity.

Authors:  Shamsah Kazani; Anna Planaguma; Emiko Ono; Matteo Bonini; Muhammad Zahid; Gautham Marigowda; Michael E Wechsler; Bruce D Levy; Elliot Israel
Journal:  J Allergy Clin Immunol       Date:  2013-04-19       Impact factor: 10.793

5.  Leukotriene B4 in cows with normal calving, and in cows with retained fetal membranes and/or uterine subinvolution.

Authors:  H Slama; D Vaillancourt; A K Goff
Journal:  Can J Vet Res       Date:  1993-10       Impact factor: 1.310

6.  Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production.

Authors:  Carrie D Fischer; Stephanie C Duquette; Bernard S Renaux; Troy D Feener; Douglas W Morck; Morley D Hollenberg; Merlyn J Lucas; Andre G Buret
Journal:  Antimicrob Agents Chemother       Date:  2014-05-12       Impact factor: 5.191

7.  On the expression and regulation of 5-lipoxygenase in human lymphocytes.

Authors:  P J Jakobsson; D Steinhilber; B Odlander; O Rådmark; H E Claesson; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

8.  Adenosine A2 receptor-induced inhibition of leukotriene B4 synthesis in whole blood ex vivo.

Authors:  E Krump; G Lemay; P Borgeat
Journal:  Br J Pharmacol       Date:  1996-04       Impact factor: 8.739

9.  Excessive leukotriene B4 in nucleus tractus solitarii is prohypertensive in spontaneously hypertensive rats.

Authors:  Hidefumi Waki; Emma B Hendy; Charles C T Hindmarch; Sabine Gouraud; Marie Toward; Sergey Kasparov; David Murphy; Julian F R Paton
Journal:  Hypertension       Date:  2012-11-19       Impact factor: 10.190

10.  Leukotrienes are upregulated and associated with human T-lymphotropic virus type 1 (HTLV-1)-associated neuroinflammatory disease.

Authors:  Bruno Caetano Trindade; Carlos Artério Sorgi; Larissa Deadame de Figueiredo Nicolete; Tathiane Maistro Malta; Mariana Tomazini Pinto; Osvaldo Massaiti Takayanagui; Dimas Tadeu Covas; Olindo Assis Martins Filho; Simone Kashima; Lúcia Helena Faccioli
Journal:  PLoS One       Date:  2012-12-20       Impact factor: 3.240
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