Literature DB >> 1319351

Biotransformation, by Enterobacter agglomerans, of pyrimidine acyclonucleosides to acyclonucleotides.

M Rutkowski1, E Korczak.   

Abstract

The ability of Enterobacter agglomerans to transform naturally occurring nucleosides into nucleotides has been utilized to transform newly synthesized pyrimidine acyclonucleosides into the corresponding acyclonucleotides. Unselected bacteria were used as the source of nucleoside phosphotransferase, the phosphate group donor being 4-nitrophenyl phosphate in the presence of Zn2+ ions. Optimal reaction conditions are outlined.

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Year:  1992        PMID： 1319351     DOI： 10.1007/bf01920246

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  [Studies on the nucleic acids. I. Quantitative paper chromatography of the ribonucleotides].

Authors:  P BOULANGER; J MONTREUIL
Journal:  Bull Soc Chim Biol (Paris)       Date:  1951

2.  Antiviral therapy.

Authors:  M S Hirsch; J C Kaplan
Journal:  Sci Am       Date:  1987-04       Impact factor: 2.142

3.  Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.

Authors:  G B Elion; P A Furman; J A Fyfe; P de Miranda; L Beauchamp; H J Schaeffer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

4.  Nucleotide analogue inhibitors of purine nucleoside phosphorylase.

Authors:  T A Krenitsky; J V Tuttle; W H Miller; A R Moorman; G F Orr; L Beauchamp
Journal:  J Biol Chem       Date:  1990-02-25       Impact factor: 5.157

5.  Growth inhibition of Kirkman-Robbins hepatoma by 1-(1,3-dihydroxy-2-propoxymethyl)-5,6-tetramethyleneuracil and possible mechanism of its biological activity.

Authors:  J Greger; M Dramiński
Journal:  Z Naturforsch C J Biosci       Date:  1989 Nov-Dec

6.  Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides.

Authors:  J M Stein; J D Stoeckler; S Y Li; R L Tolman; M MacCoss; A Chen; J D Karkas; W T Ashton; R E Parks
Journal:  Biochem Pharmacol       Date:  1987-04-15       Impact factor: 5.858

7.  Acyclonucleosides: acyclobenzimidazole nucleoside and nucleotide analogues and conformations of the acyclic chains by means of NMR spectroscopy.

Authors:  Z Kazimierczuk; R Stolarski; D Shugar
Journal:  Acta Biochim Pol       Date:  1984       Impact factor: 2.149

Review 8.  Mechanism of action and selectivity of acyclovir.

Authors:  G B Elion
Journal:  Am J Med       Date:  1982-07-20       Impact factor: 4.965

9.  Acyclonucleoside analogues consisting of 5- and 5,6-substituted uracils and different acyclic chains: inhibitory properties vs purified E. coli uridine phosphorylase.

Authors:  A K Drabikowska; L Lissowska; M Draminski; A Zgit-Wroblewska; D Shugar
Journal:  Z Naturforsch C J Biosci       Date:  1987-03

10.  [Adenosine transformation into adenosine-5'-monophosphate by intact Erwinia herbicola cells].

Authors:  I L Popov; V N Baraĭ; A I Zinchenko; S P Chernov; E I Kvasiuk
Journal:  Antibiot Med Biotekhnol       Date:  1985-08
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