Literature DB >> 1319210

The Ku complex is modulated in response to viral infection and other cellular changes.

J P Quinn1, J Simpson, A R Farina.   

Abstract

The complex of Ku with DNA is demonstrated to have multiple forms as assayed by gel retardation analysis. In CV1 cells this variation of complex can be modulated in response to viral infection with SV40. By Western blot analysis, a correlation can be made between modification of the complex formed on DNA in response to viral infection with variation of the 85 kDa subunit of Ku. Modification of the 85 kDa subunit can also be seen when cells are exposed to various extracellular stimuli including variation in serum levels, PMA and CaPO4.

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Year:  1992        PMID: 1319210     DOI: 10.1016/0167-4781(92)90074-a

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  3 in total

1.  Production and characterization of recombinant human Ku antigen.

Authors:  M Ono; P W Tucker; J D Capra
Journal:  Nucleic Acids Res       Date:  1994-09-25       Impact factor: 16.971

2.  Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen.

Authors:  E Genersch; C Eckerskorn; F Lottspeich; C Herzog; K Kühn; E Pöschl
Journal:  EMBO J       Date:  1995-02-15       Impact factor: 11.598

3.  Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells.

Authors:  Charles A Gullo; Feng Ge; Geraline Cow; Gerrard Teoh
Journal:  Cancer Cell Int       Date:  2008-04-29       Impact factor: 5.722

  3 in total

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