Avianized rabies virus vaccination in man.

This paper describes the results of three experiments in which 98 volunteers were inoculated intramuscularly with living avianized rabies virus of the Flury strain, modified by adaptation to chick embryo; their reactions were compared with those of 31 other persons either inoculated with normal-embryo material, or undergoing Pasteur treatment. Immune response was estimated by determination of the development of neutralizing antibodies. These observations show that Flury-virus vaccine can be used without untoward effects for the immunization of man against rabies, but give no clear indication as to the best method for the administration of this vaccine.