Literature DB >> 1318257

Trisomy 12 and 4 in a thecoma of the ovary.

K Mrózek1, J Limon, J Debniak, J Emerich.   

Abstract

Cytogenetic analysis of short-term tissue culture from a thecoma of the ovary demonstrated the presence of trisomies of chromosomes 12 and 4 in all analyzed cells. Our finding confirms the consistency with which trisomy 12 is observed in benign sex cord/stromal tumors and suggests that trisomy 4 may be a second event in tumorigenesis of thecoma.

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Year:  1992        PMID: 1318257     DOI: 10.1016/0090-8258(92)90493-3

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  2 in total

1.  Imbalances of chromosomes 4, 9, and 12 are recurrent in the thecoma-fibroma group of ovarian stromal tumors.

Authors:  Renae C Streblow; Alicia J Dafferner; Marilu Nelson; Mavis Fletcher; William W West; Rachel K Stevens; Zoran Gatalica; Deborah Novak; Julia A Bridge
Journal:  Cancer Genet Cytogenet       Date:  2007-10-15

2.  Consistent numerical chromosome aberrations in thecofibromas of the ovary.

Authors:  Francesca Micci; Lisbeth Haugom; Vera M Abeler; Claes G Tropé; Håvard E Danielsen; Sverre Heim
Journal:  Virchows Arch       Date:  2008-03       Impact factor: 4.064

  2 in total

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