Literature DB >> 13175

Dihydroxylated metabolites of cannabinol formed by rat liver in vitro.

K Fonseka, M Widman.   

Abstract

Cannabinol (CBN) was metabolized in vitro by a 10,000 g supernatant from rat liver. After removal of unchanged CBN and its monohydroxylated metabolites four dihydroxylated metabolites were isolated. By nuclear magnetic resonance and mass spectrometry the compounds were identified as 1'',7-dihydroxy-CBN. Side chain hydroxylation occurred predominantly at C-4'' anc C-3''.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 13175     DOI: 10.1111/j.2042-7158.1977.tb11229.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  1 in total

1.  Metabolism and clearance of proxicromil--studies in rat, hamster, rabbit, dog, squirrel monkey, cynomolgus monkey, baboon and man.

Authors:  D A Smith; M G Neale
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1983 Jul-Sep       Impact factor: 2.441

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.