Literature DB >> 1317301

Differential expression of two sodium channel subtypes in human brain.

C M Lu1, J Han, T A Rado, G B Brown.   

Abstract

Two partial human brain sodium channel cDNA sequences (designated HBSC I and II) have been cloned and mapped to chromosome 2q23-2q24 by chromosome microdissection-PCR (CMPCR). The distribution of HBSC I and II mRNA in human brain was studied by means of a novel approach based on the ligase detection reaction. These studies demonstrate that HBSC I and II mRNA is heterogeneously distributed in brain, and that the relative ratio of the two forms can vary as much as 7-fold between different regions.

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Year:  1992        PMID: 1317301     DOI: 10.1016/0014-5793(92)80476-w

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  5 in total

1.  Isolation of the 5'-flanking region for human brain sodium channel subtype II alpha-subunit.

Authors:  C M Lu; J S Eichelberger; M L Beckman; S D Schade; G B Brown
Journal:  J Mol Neurosci       Date:  1998-12       Impact factor: 3.444

2.  Hydrophobic free energy eigenfunctions of pore, channel, and transporter proteins contain beta-burst patterns.

Authors:  K A Selz; A J Mandell; M F Shlesinger
Journal:  Biophys J       Date:  1998-11       Impact factor: 4.033

3.  QUANTITATIVE RT-PCR ANALYSES OF FIVE EVOLUTIONARY CONSERVED GENES IN ALLIGATOR BRAINS DURING DEVELOPMENT.

Authors:  Sarah M Wilson; Tianli Zhu; Rajesh Khanna; Michael B Pritz
Journal:  Transl Neurosci       Date:  2011-12       Impact factor: 1.757

4.  A second locus for familial generalized epilepsy with febrile seizures plus maps to chromosome 2q21-q33.

Authors:  S Baulac; I Gourfinkel-An; F Picard; M Rosenberg-Bourgin; J F Prud'homme; M Baulac; A Brice; E LeGuern
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

5.  Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism.

Authors:  J T Prchal; J F Prchal; M Belickova; S Chen; Y Guan; G L Gartland; M D Cooper
Journal:  J Exp Med       Date:  1996-02-01       Impact factor: 14.307

  5 in total

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