Literature DB >> 1317238

Are polioviruses a cause of schizophrenia?

J M Eagles1.   

Abstract

Pre-natal infection with polioviruses could contribute to the subsequent development of schizophrenia. The hypothesis draws support from the declining incidence of schizophrenia, the excess of schizophrenic winter births, and the increased rates of schizophrenia among West Indian immigrants. There are parallels with other late sequelae of poliovirus infections. These postulations generate a testable hypothesis of a genetic link between schizophrenia and susceptibility to poliomyelitis.

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Year:  1992        PMID: 1317238     DOI: 10.1192/bjp.160.5.598

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  4 in total

1.  Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research.

Authors:  R F Squires; E Saederup
Journal:  Neurochem Res       Date:  2000-12       Impact factor: 3.996

Review 2.  Can environmental factors explain the epidemiology of schizophrenia in immigrant groups?

Authors:  S Gupta
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  1993-11       Impact factor: 4.328

Review 3.  Schizophrenia: solving the puzzle.

Authors:  B D Kelly; E O'Callaghan; A Lane; C Larkin
Journal:  Ir J Med Sci       Date:  2003 Jan-Mar       Impact factor: 1.568

4.  Coxsackievirus-induced acute neonatal central nervous system disease model.

Authors:  Lulu Wang; Changyuan Dong; Dong-E Chen; Zhen Song
Journal:  Int J Clin Exp Pathol       Date:  2014-02-15
  4 in total

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