Literature DB >> 1317146

Novel method for evaluating antiviral drugs against human cytomegalovirus in mice.

L B Allen1, S X Li, G Arnett, B Toyer, W M Shannon, M G Hollingshead.   

Abstract

A virus-host cell system in which human cytomegalovirus-infected human cells are entrapped in agarose plugs has been developed. This model provides an inexpensive method for the in vivo evaluation (with outbred, immunocompetent mice) of antiviral drugs against human viruses such as cytomegalovirus that replicate primarily or only in human cells.

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Year:  1992        PMID： 1317146      PMCID： PMC189256          DOI： 10.1128/AAC.36.1.206

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  Feasibility of cellular microencapsulation technology for evaluation of anti-human immunodeficiency virus drugs in vivo.

Authors:  J McMahon; S Schmid; O Weislow; S Stinson; R Camalier; R Gulakowski; R Shoemaker; R Kiser; D Dykes; S Harrison
Journal:  J Natl Cancer Inst       Date:  1990-11-21       Impact factor: 13.506

Review 2.  The indirect effects of cytomegalovirus infection on the outcome of organ transplantation.

Authors:  R H Rubin
Journal:  JAMA       Date:  1989 Jun 23-30       Impact factor: 56.272

3.  Microencapsulated tumor assay: new short-term assay for in vivo evaluation of the effects of anticancer drugs on human tumor cell lines.

Authors:  E Gorelik; A Ovejera; R Shoemaker; A Jarvis; M Alley; R Duff; J Mayo; R Herberman; M Boyd
Journal:  Cancer Res       Date:  1987-11-01       Impact factor: 12.701

4.  Cytomegalovirus pneumonitis in patients with AIDS. Findings in an autopsy series.

Authors:  J M Wallace; J Hannah
Journal:  Chest       Date:  1987-08       Impact factor: 9.410

5.  Antiviral effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine against cytomegalovirus infection in a guinea pig model.

Authors:  C K Fong; S D Cohen; S McCormick; G D Hsiung
Journal:  Antiviral Res       Date:  1987-01       Impact factor: 5.970

6.  Increased efficacy of ganciclovir in combination with foscarnet against cytomegalovirus and herpes simplex virus type 2 in vitro and in vivo.

Authors:  V R Freitas; E B Fraser-Smith; T R Matthews
Journal:  Antiviral Res       Date:  1989-11       Impact factor: 5.970

7.  Effect of acyclovir and phosphonoformate on cytomegalovirus infection in guinea pigs.

Authors:  H L Lucia; B P Griffith; G D Hsiung
Journal:  Intervirology       Date:  1984       Impact factor: 1.763

8.  Effect of acyclovir treatment on acute and chronic murine cytomegalovirus infection.

Authors:  L A Glasgow; J T Richards; E R Kern
Journal:  Am J Med       Date:  1982-07-20       Impact factor: 4.965
  8 in total
  5 in total

1.  Oral activity of a methylenecyclopropane analog, cyclopropavir, in animal models for cytomegalovirus infections.

Authors:  Earl R Kern; Deborah J Bidanset; Caroll B Hartline; Zhaohua Yan; Jiri Zemlicka; Debra C Quenelle
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

2.  Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir.

Authors:  Earl R Kern; Deborah J Collins; W Brad Wan; James R Beadle; Karl Y Hostetler; Debra C Quenelle
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

3.  A model of human cytomegalovirus infection in severe combined immunodeficient mice.

Authors:  Fernando J Bravo; Rhonda D Cardin; David I Bernstein
Journal:  Antiviral Res       Date:  2007-07-10       Impact factor: 5.970

4.  Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.

Authors:  Simone Thomas; Sebastian Klobuch; Jürgen Podlech; Bodo Plachter; Petra Hoffmann; Angelique Renzaho; Matthias Theobald; Matthias J Reddehase; Wolfgang Herr; Niels A W Lemmermann
Journal:  PLoS Pathog       Date:  2015-07-16       Impact factor: 6.823

5.  A mouse model of interstitial pneumonitis induced by murine cytomegalovirus infection after allogeneic skin transplantation.

Authors:  Dequn Ni; Haiyang Yu; Wei Zhang; Lin Gan; Jiqiang Zhao; Mingli Wang; Jason Chen
Journal:  Biomed Res Int       Date:  2013-07-02       Impact factor: 3.411
  5 in total

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